Interactive views of phylogenetic sequence trees for conserved domain models are available in NCBI-curated domains. If your domain of interest has an NCBI-curated model, you can retrieve it in the following way:

• Search the Conserved Domain Database for your term(s) of interest, e.g., voltage gated chloride channel.


• Limit your search results to NCBI-curated domains, which include interactive phylogenetic sequence trees, by adding the following criterion to your query at the top of the search results page:    AND cdd[Database],   and press the "Go" button.


• Click on the accession number of any domain of interest on the search results page to open its CD summary page (example shown below).
  
• A low resolution view of the phylogenetic sequence tree is embedded in the Sequence Cluster section of the CD summary page. Press the Zoom in button to view a higher resolution tree within the current browser window, or the Detailed View button to open a new browser window, which contains the higher resolution as well as options to highlight subsets of proteins by domain family tree node.


• We no longer provide interactive visualization of the phylogenetic sequence tree in the <CDTree program, as support for CDTree has ended.


• It is also possible to embed a protein query sequence in a conserved domain model's multiple sequence alignment.