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8VHD:
Crystal Structure of Human IDH1 R132Q in complex with NADPH and Isocitrate
PDB ID:
8VHD
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MMDB ID:
245945
PDB Deposition Date:
2023/12/31
Updated in MMDB:
2024/04
Experimental Method:
x-ray diffraction
Resolution:
2.38 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 8VHD: dimeric; determined by author and by software (PISA)
Molecular Components in 8VHD
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Isocitrate Dehydrogenase [nadp] Cytoplasmic
(Gene symbol:
IDH1
)
Chemicals and Non-standard biopolymers (7 molecules)
1
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
IODIDE ION
3
2
CALCIUM ION
4
1
GLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303