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Microarray analysis of the hyperthermophilic archaeon Pyrococcus furiosus exposed to gamma irradiation

(Submitter supplied) The remarkable survival of the hyperthermophilic archaeon Pyrococcus furiosus to ionizing radiation was previously demonstrated. Using a time course study and whole-genome microarray analyses of mRNA transcript levels, the genes and regulatory pathways involved in the repair of lesions produced by ionizing irradiation (oxidative damage and DNA strand breaks) in P. furiosus were investigated. Data analyses showed that radA, encoding the archaeal homolog of the RecA/Rad51 recombinase, was moderately up regulated by irradiation and that a putative DNA-repair gene cluster was specifically induced by exposure to ionizing radiation. more...
Organism:
Pyrococcus furiosus
Type:
Expression profiling by array
Dataset:
GDS2469
Platform:
GPL3926
21 Samples
Download data
Series
Accession:
GSE5919
ID:
200005919

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