GPL6884[Accession] - GEO DataSets - NCBI

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Select item 2002274881.

Human CCR6+ Th cells show both an extended stable gradient of Th17 activity and imprinted plasticity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; unidentified

Type:: Methylation profiling by genome tiling array; Expression profiling by array; Expression profiling by high throughput sequencing; Other

4 related Platforms
159 Samples

Download data: CSV, H5, IDAT, TXT

Series

Accession:: GSE227488

ID:: 200227488

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2002274872.

Human CCR6+ Th cells show both an extended stable gradient of Th17 activity and imprinted plasticity [BeadChipHumanWG-6]

(Submitter supplied) Th17 cells have been investigated in mice primarily for their contributions to autoimmune diseases. However, the pathways of differentiation of Th17 and related Th cells (type 17 cells) and the structure of the type 17 memory population in humans are not well understood; such understanding is critical for manipulating these cells in vivo. By exploiting differences in levels of surface CCR6, we found that human type 17 memory cells, including individual T cell clonotypes, form an elongated continuum of type 17 character along which cells can be driven by increasing RORt. more...

Organism:: Homo sapiens; unidentified

Type:: Expression profiling by array

Platform:: GPL6884
81 Samples

Download data: TXT

Series

Accession:: GSE227487

ID:: 200227487

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001659533.

Glutamate pathway dysfunction in MELAS syndrome is alleviated by ketogenic diet

(Submitter supplied) The development of mitochondrial medicine is greatly impaired by the lack of knowledge and identification of efficient therapeutic routes targeting mitochondria. To better understand the pathophysiology of MELAS syndrome, neuronal cybrid cells, carrying different mutant loads of the m.3243A>G mutation, were investigated by a metabolomics and transcriptomics combined approach. Specific signatures, identifying MELAS biochemical biomarkers, disclosed the glutamate pathway as a culprit mechanism, establishing a strong correlation between glutamate concentrations and the m.3243A>G heteroplasmy levels. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
8 Samples

Download data: IDAT

Series

Accession:: GSE165953

ID:: 200165953

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001373934.

Genome-wide analysis of gene expression after knockdown of KDM5B in melanoma cells.

(Submitter supplied) Analysis of the effects of KDM5B in melanoma cells at gene expression level. Knockdown of KDM5B provides important information about potential target genes of KDM5B.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
2 Samples

Download data: IDAT

Series

Accession:: GSE137393

ID:: 200137393

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001866905.

HDAC6 regulates NF-κB signalling by HDAC-dependent and independent mechanisms to control chondrocyte IL-1-induced MMP and inflammatory gene expression

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
12 Samples

Series

Accession:: GSE186690

ID:: 200186690

Analyze with GEO2R

Select item 2001866896.

HDAC6 regulates NF-κB signalling by HDAC-dependent and independent mechanisms to control chondrocyte IL-1-induced MMP and inflammatory gene expression [TSA exp]

(Submitter supplied) Analysis of the effect of HDAC inhibitor TSA on IL-1-induced gene expression in SW1353 chondrocytes.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
4 Samples

Download data: TXT

Series

Accession:: GSE186689

ID:: 200186689

Analyze with GEO2R

Select item 2001866887.

HDAC6 regulates NF-κB signalling by HDAC-dependent and independent mechanisms to control chondrocyte IL-1-induced MMP and inflammatory gene expression [HDAC siRNA exp]

(Submitter supplied) Analysis of the effect of HDAC6 knockdown on IL-1-induced gene expression in SW1353 chondrocytes.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
8 Samples

Download data: TXT

Series

Accession:: GSE186688

ID:: 200186688

Analyze with GEO2R

Select item 2001334058.

Effects of successful aerobic and strength training on gene expression of lymphomonocytes of stable CAD patients

(Submitter supplied) Analysis of impact of successful combined aerobic and strength training intervention of CAD patients on lymphomonocyte gene expression. The purpose of this study was to identify the most up/down-regulated gene sets related to the training to increase our knowledge on the mechanisms mediating the exercise-induced effects.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
14 Samples

Download data: TXT

Series

Accession:: GSE133405

ID:: 200133405

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001461149.

Combining imaging- and gene-based hypoxia biomarkers in cervical cancer improves prediction of treatment failure independent of intratumor heterogeneity

(Submitter supplied) Emerging biomarkers based on medical images and molecular characterization of tumor biopsies open up for combining the two disciplines and exploiting their synergy in treatment planning. We compared pretreatment classification of cervical cancer patients by two previously validated imaging- and gene-based hypoxia biomarkers, evaluated the influence of intratumor heterogeneity, and investigated the benefit of combining them in prediction of treatment failure. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL10558 GPL6884
142 Samples

Download data: TXT

Series

Accession:: GSE146114

ID:: 200146114

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010016610.

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (TB Datasets)

(Submitter supplied) Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
34 Samples

Download data: TXT

Series

Accession:: GSE100166

ID:: 200100166

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010016511.

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (Staph Datasets)

(Submitter supplied) Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
143 Samples

Download data: TXT

Series

Accession:: GSE100165

ID:: 200100165

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010016412.

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (SoJIA Datasets)

(Submitter supplied) Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
85 Samples

Download data: TXT

Series

Accession:: GSE100164

ID:: 200100164

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010016313.

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (SLE Datasets)

(Submitter supplied) Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
69 Samples

Download data: TXT

Series

Accession:: GSE100163

ID:: 200100163

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010016214.

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (MS Datasets)

(Submitter supplied) Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
56 Samples

Download data: TXT

Series

Accession:: GSE100162

ID:: 200100162

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010016115.

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (RSV Datasets)

(Submitter supplied) Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
84 Samples

Download data: TXT

Series

Accession:: GSE100161

ID:: 200100161

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010016016.

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (Flu Datasets)

(Submitter supplied) Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
39 Samples

Download data: TXT

Series

Accession:: GSE100160

ID:: 200100160

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010015917.

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (Sepsis Datasets)

(Submitter supplied) Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
47 Samples

Download data: TXT

Series

Accession:: GSE100159

ID:: 200100159

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010015818.

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (Melanoma Datasets)

(Submitter supplied) Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
27 Samples

Download data: TXT

Series

Accession:: GSE100158

ID:: 200100158

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010015719.

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (Pregnancy Datasets)

(Submitter supplied) Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
45 Samples

Download data: TXT

Series

Accession:: GSE100157

ID:: 200100157

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20010015620.

A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring (B-cell deficiency Datasets)

(Submitter supplied) Development of a cost-effective and practical targeted transcriptional fingerprinting assay (TFA) for monitoring a diverse repertoire of immune responses identified in the human blood transcriptome relying on a modular transcriptional repertoire built on the basis of variations in transcript abundance measured on a genome wide scale in the blood of nearly 1000 subjects across 16 immunologic conditions.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6884
33 Samples

Download data: TXT

Series

Accession:: GSE100156

ID:: 200100156

PubMed Full text in PMC Similar studies Analyze with GEO2R

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