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Items: 1 to 20 of 40

1.

Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL

(Submitter supplied) The Bruton tyrosine kinase (BTK) inhibitor ibrutinib has substantially improved therapeutic options for chronic lymphocytic leukemia (CLL). Although ibrutinib is not curative, it has a profound effect on CLL cells and may create new pharmacologically exploitable vulnerabilities. To identify such vulnerabilities, we developed a systematic approach that combines epigenome profiling (charting the gene-regulatory basis of cell state) with single-cell chemosensitivity profiling (quantifying cell-type-specific drug response) and bioinformatic data integration. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL20301
38 Samples
Download data: BIGWIG, CSV, NARROWPEAK
Series
Accession:
GSE100672
ID:
200100672
2.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
3.

ATAC-seq for patient CLL9 during Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691021
ID:
302691021
4.

ATAC-seq for patient CLL9 before Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691020
ID:
302691020
5.

ATAC-seq for patient CLL7 during Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691019
ID:
302691019
6.

ATAC-seq for patient CLL7 before Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691018
ID:
302691018
7.

ATAC-seq for patient CLL6 during Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691017
ID:
302691017
8.

ATAC-seq for patient CLL6 before Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691016
ID:
302691016
9.

ATAC-seq for patient CLL5 before Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691015
ID:
302691015
10.

ATAC-seq for patient CLL5 during Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691014
ID:
302691014
11.

ATAC-seq for patient CLL4 during Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691013
ID:
302691013
12.

ATAC-seq for patient CLL4 before Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691012
ID:
302691012
13.

ATAC-seq for patient CLL3 during Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691011
ID:
302691011
14.

ATAC-seq for patient CLL3 before Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691010
ID:
302691010
15.

ATAC-seq for patient CLL21 before Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691009
ID:
302691009
16.

ATAC-seq for patient CLL21 during Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691008
ID:
302691008
17.

ATAC-seq for patient CLL20 during Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691007
ID:
302691007
18.

ATAC-seq for patient CLL20 before Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691006
ID:
302691006
19.

ATAC-seq for patient CLL2 before Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691005
ID:
302691005
20.

ATAC-seq for patient CLL2 during Ibrutinib treatment

Organism:
Homo sapiens
Source name:
Primary peripheral blood mononucleated cells (PBMC) from chronic lymphocytic leukemia patient
Platform:
GPL20301
Series:
GSE100672
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM2691004
ID:
302691004
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Supplemental Content

db=gds|term=GSE100672[Accession]|query=1|qty=2|blobid=MCID_67dc342ae6bb29401370662d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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