GSE101166[Accession] - GEO DataSets

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Items: 10

Select item 2001011661.

CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [AGOpulldownRNAseq.sm]

(Submitter supplied) >80% of a large number of tested siRNAs and shRNAs targeting CD95 or CD95 ligand (CD95L) induce a form of cell death that is characterized by the simultaneous activation of multiple death pathways and preferentially affects transformed and cancer stem cells. We now show that these si/shRNAs kill cancer cells through canonical RNAi by targeting the 3’UTR of critical survival genes in a unique form of off-target effect. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL20301
8 Samples

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Series

Accession:: GSE101166

ID:: 200101166

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000203012.

Illumina HiSeq 4000 (Homo sapiens)

Organism:: Homo sapiens

8769 Series
199974 Samples

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Platform

Accession:: GPL20301

ID:: 100020301

Select item 3027000653.

pLenti HCT116 cells rep 2

Organism:: Homo sapiens

Source name:: ATCC CCL-247

Platform:: GPL20301
Series:: GSE87817 GSE101166

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Sample

Accession:: GSM2700065

ID:: 302700065

SRA Run Selector

Select item 3027000644.

pLenti HCT116 cells rep 1

Organism:: Homo sapiens

Source name:: ATCC CCL-247

Platform:: GPL20301
Series:: GSE87817 GSE101166

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Sample

Accession:: GSM2700064

ID:: 302700064

SRA Run Selector

Select item 3027000635.

pLenti HCT116 Drosha KO cells rep 2

Organism:: Homo sapiens

Source name:: ATCC CCL-247; Drosha KO cells provided by Narry Kim, ref: Kim Y.K., Kim B., Kim V.N. (2016). Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis. Proc Natl Acad Sci U S A. 113(13):E1881-9.

Platform:: GPL20301
Series:: GSE87817 GSE101166

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Sample

Accession:: GSM2700063

ID:: 302700063

SRA Run Selector

Select item 3027000626.

pLenti HCT116 Drosha KO cells rep 1

Organism:: Homo sapiens

Source name:: ATCC CCL-247; Drosha KO cells provided by Narry Kim, ref: Kim Y.K., Kim B., Kim V.N. (2016). Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis. Proc Natl Acad Sci U S A. 113(13):E1881-9.

Platform:: GPL20301
Series:: GSE87817 GSE101166

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Sample

Accession:: GSM2700062

ID:: 302700062

SRA Run Selector

Select item 3027000617.

CD95LMUTNP overexpressed in HCT116 cells rep 2

Organism:: Homo sapiens

Source name:: ATCC CCL-247

Platform:: GPL20301
Series:: GSE87817 GSE101166

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Sample

Accession:: GSM2700061

ID:: 302700061

SRA Run Selector

Select item 3027000608.

CD95LMUTNP overexpressed in HCT116 cells rep 1

Organism:: Homo sapiens

Source name:: ATCC CCL-247

Platform:: GPL20301
Series:: GSE87817 GSE101166

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Sample

Accession:: GSM2700060

ID:: 302700060

SRA Run Selector

Select item 3027000599.

CD95LMUTNP overexpressed in HCT116 Drosha KO cells rep 2

Organism:: Homo sapiens

Source name:: ATCC CCL-247; Drosha KO cells provided by Narry Kim, ref: Kim Y.K., Kim B., Kim V.N. (2016). Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis. Proc Natl Acad Sci U S A. 113(13):E1881-9.

Platform:: GPL20301
Series:: GSE87817 GSE101166

Download data

Sample

Accession:: GSM2700059

ID:: 302700059

SRA Run Selector

Select item 30270005810.

CD95LMUTNP overexpressed in HCT116 Drosha KO cells rep 1

Organism:: Homo sapiens

Source name:: ATCC CCL-247; Drosha KO cells provided by Narry Kim, ref: Kim Y.K., Kim B., Kim V.N. (2016). Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis. Proc Natl Acad Sci U S A. 113(13):E1881-9.