GSE219136[Accession] - GEO DataSets - NCBI

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Items: 8

Select item 2002191361.

Screen for genes showing synthetic lethality with NF2 in Schwannoma [Other]

(Submitter supplied) Neurofibromatosis Type II is a genetic condition caused by loss of the NF2 gene, resulting in activation of the YAP/TAZ pathway and recurrent growth of benign tumors from Schwann cells, the glia of the peripheral nervous system. Unfortunately, no pharmacological therapy is currently available for NFII. Here, we undertake a genome-wide CRISPR/cas9 screen to search for synthetic-lethal genes that, when inhibited, cause death of NF2 mutant cells but not NF2 wildtype cells. more...

Organism:: Homo sapiens

Type:: Other

Platform:: GPL11154
6 Samples

Download data: TXT

Series

Accession:: GSE219136

ID:: 200219136

Select item 1000111542.

Illumina HiSeq 2000 (Homo sapiens)

Organism:: Homo sapiens

10422 Series
180547 Samples

Platform

Accession:: GPL11154

ID:: 100011154

Select item 3067744623.

Schwann Cells, NF2-KO, Passage 7, Replicate 2

Organism:: Homo sapiens

Source name:: Schwannoma

Platform:: GPL11154
Series:: GSE219136 GSE219141

Sample

Accession:: GSM6774462

ID:: 306774462

SRA Run Selector

Select item 3067744614.

Schwann Cells, NF2-KO, Passage 7, Replicate 1

Organism:: Homo sapiens

Source name:: Schwannoma

Platform:: GPL11154
Series:: GSE219136 GSE219141

Sample

Accession:: GSM6774461

ID:: 306774461

SRA Run Selector

Select item 3067744605.

Schwann Cells, NF2-KO, Passage 0

Organism:: Homo sapiens

Source name:: Schwannoma

Platform:: GPL11154
Series:: GSE219136 GSE219141

Sample

Accession:: GSM6774460

ID:: 306774460

SRA Run Selector

Select item 3067744596.

Schwann Cells, NF2-WT, Passage 7, Replicate 2

Organism:: Homo sapiens

Source name:: Schwannoma

Platform:: GPL11154
Series:: GSE219136 GSE219141

Sample

Accession:: GSM6774459

ID:: 306774459

SRA Run Selector

Select item 3067744587.

Schwann Cells, NF2-WT, Passage 7, Replicate 1

Organism:: Homo sapiens

Source name:: Schwannoma

Platform:: GPL11154
Series:: GSE219136 GSE219141

Sample

Accession:: GSM6774458

ID:: 306774458

SRA Run Selector

Select item 3067744578.

Schwann Cells, NF2-WT, Passage 0

Organism:: Homo sapiens

Source name:: Schwannoma

Platform:: GPL11154
Series:: GSE219136 GSE219141

Sample

Accession:: GSM6774457

ID:: 306774457

SRA Run Selector

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