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Items: 1 to 20 of 41

1.

PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification

(Submitter supplied) Heterotopic ossification (HO) occurs following mechanical trauma, burns, or congenitally in patients suffering from fibrodysplasia ossificans progressiva (FOP). Recently, we demonstrated that inhibitors of phosphatidyl-inositol 3-kinase alpha (PI3Kα), including the already marketed BYL719/Alpelisib/Piqray, may become a useful therapy for patients undergoing HO. In this study, we have confirmed these results and optimized the timing of administration of BYL719. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
39 Samples
Download data: CSV
Series
Accession:
GSE237512
ID:
200237512

Analyze with GEO2R

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
14841 Series
882721 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

hMSC R206H, BYL719, BMP6, 4

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901218
ID:
307901218

SRA Run Selector

4.

hMSC R206H, BYL719, BMP6, 3

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901217
ID:
307901217

SRA Run Selector

5.

hMSC R206H, BYL719, BMP6, 2

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901216
ID:
307901216

SRA Run Selector

6.

hMSC R206H, BYL719, BMP6, 1

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901215
ID:
307901215

SRA Run Selector

7.

hMSC R206H, DMSO, BMP6, 4

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901214
ID:
307901214

SRA Run Selector

8.

hMSC R206H, DMSO, BMP6, 3

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901213
ID:
307901213

SRA Run Selector

9.

hMSC R206H, DMSO, BMP6, 2

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901212
ID:
307901212

SRA Run Selector

10.

hMSC R206H, DMSO, BMP6, 1

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901211
ID:
307901211

SRA Run Selector

11.

hMSC R206H, DMSO, Vehicle, 4

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901210
ID:
307901210

SRA Run Selector

12.

hMSC R206H, DMSO, Vehicle, 2

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901209
ID:
307901209

SRA Run Selector

13.

hMSC R206H, DMSO, Vehicle, 1

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901208
ID:
307901208

SRA Run Selector

14.

hMSC WT, BYL719, Activin A, 4

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901207
ID:
307901207

SRA Run Selector

15.

hMSC WT, BYL719, Activin A, 3

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901206
ID:
307901206

SRA Run Selector

16.

hMSC WT, BYL719, Activin A, 2

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901205
ID:
307901205

SRA Run Selector

17.

hMSC WT, BYL719, Activin A, 1

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901204
ID:
307901204

SRA Run Selector

18.

hMSC WT, DMSO, Activin A, 4

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901203
ID:
307901203

SRA Run Selector

19.

hMSC WT, DMSO, Activin A, 3

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901202
ID:
307901202

SRA Run Selector

20.

hMSC WT, DMSO, Activin A, 2

Organism:
Homo sapiens
Source name:
bone marrow derived
Platform:
GPL24676
Series:
GSE237512
Download data
Sample
Accession:
GSM7901201
ID:
307901201

SRA Run Selector

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