GSE243055[Accession] - GEO DataSets

Select item 2002430551.

A novel t(X;21) (p11.4;q22.12) translocation adds to the role of BCOR and RUNX1 in Myelodysplastic Syndromes/Acute Myeloid Leukemias [Copy number analysis]

(Submitter supplied) In this study we present a thus far undescribed, reciprocal, unbalanced chromosomal translocation between the long arm of chromosome 21 and the short arm of chromosome X, t(X;21)(p11.4;q22.12), in five cases with Myelodysplastic Syndromes and Acute Myeloid Leukemias (MDS/AML). The translocation was isolated or accompanied by one additional change and is not generating a fusion gene. Deletion of RUNX1 at chromosome 21 and of BCOR at chromosome X was shown by Fluorescence In Situ Hybridization (FISH) and Single Nucleotide Polymorphism array (SNPa) analysis. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by SNP array

Platform:: GPL16131
4 Samples

Download data: CEL, CYCHP

Series

Accession:: GSE243055

ID:: 200243055

Select item 1000161312.

[CytoScanHD_Array] Affymetrix CytoScan HD Array

(Submitter supplied) #%create_date=2011-12-01 GMT-08:00 10:25:44 #%chip_type=CytoScanHD_Array #%genome-species=Homo sapiens #%genome-version=hg19 #%genome-version-ucsc=hg19 #%genome-version-ncbi=GRCh37 #%genome-version-create_date=2009-02-00 #%dbSNP_date=2010-09-23 #%dbSNP_version=132 #%dgv-date=2010-10-00 #%dgv-version=10 #%hapmap-date=2008-01-08 #%hapmap-version=23 #%netaffx-annotation-date=2011-12-01 #%netaffx-annotation-netaffx-build=32.1 #%netaffx-annotation-tabular-format-version=1.0 #%netaffx-annotation-docgen-method=com.affymetrix.database.docgen.DocGenDriver #%netaffx-annotation-docgen-version=cluster_friendly_submission #%create_date=2011-12-01 GMT-08:00 10:25:09 #%chip_type=CytoScanHD_Array #%genome-species=Homo sapiens #%genome-version=hg19 #%genome-version-ucsc=hg19 #%genome-version-ncbi=GRCh37 #%genome-version-create_date=2009-02-00 #%dbSNP_date=2010-09-23 #%dbSNP_version=132 #%dgv-date=2010-10-00 #%dgv-version=10 #%netaffx-annotation-date=2011-12-01 #%netaffx-annotation-netaffx-build=32.1 #%netaffx-annotation-tabular-format-version=1.0 #%netaffx-annotation-docgen-method=com.affymetrix.database.docgen.DocGenDriver #%netaffx-annotation-docgen-version=cluster_friendly_submission ##This database/product contains information from the Online Mendelian Inheritance in Man(R) (OMIM(R)) database, which has been obtained under a license from the Johns Hopkins University. more...