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Items: 4

1.

Function and mechanism of PAPOLA-mediated poly(A) lengthening in leukemia [RIP-Seq]

(Submitter supplied) The polyadenylation of mRNA is pivotal for mRNA stability and efficient mRNA translation. The length of poly(A) tail is dynamically changed under various physiological conditions; however, the functions and mechanisms of aberrant poly(A) length control in cancers remain poorly understood. Here we uncovered the aberrant lengthening of poly(A) tail and particularly upregulated expression of poly(A) polymerase alpha (PAPOLA) in acute myeloid leukemia (AML), and the elevated PAPOLA expression significantly correlated with unfavorable AML outcomes. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL20301
2 Samples
Download data: TXT
Series
Accession:
GSE255603
ID:
200255603

2.

Illumina HiSeq 4000 (Homo sapiens)

Organism:
Homo sapiens
9284 Series
214822 Samples
Download data
Platform
Accession:
GPL20301
ID:
100020301

3.

shPAPOLA

Organism:
Homo sapiens
Source name:
Leukemia
Platform:
GPL20301
Series:
GSE255603 GSE255668
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Sample
Accession:
GSM8075896
ID:
308075896

SRA Run Selector

4.

shNS

Organism:
Homo sapiens
Source name:
Leukemia
Platform:
GPL20301
Series:
GSE255603 GSE255668
Download data
Sample
Accession:
GSM8075895
ID:
308075895

SRA Run Selector

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db=gds|term=GSE255603[Accession]|query=1|qty=2|blobid=MCID_698643c7ef03752f27aa514e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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