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Items: 6

1.

Pharmaceutical inhibition of RAS overcomes cytokine mediated resistance to FLT3 inhibition in FLT3-ITD+ AML [ChIP-seq II]

(Submitter supplied) AML is characterised by a variety of co-occurring driver mutations in genes associated with cell signallingand growth regulationsuch as the FLT3-ITD. Inhibitors targeting FLT3 (FLT3i) are beingused to treat FLT3-ITD+ patients but most relapse.By profiling the gene regulatory networks of samples from patients before and after FLT3i treatment weobservedan increase in AP-1 mediated and a loss of RUNX1 mediated connections in treatment resistant cells. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL30173
4 Samples
Download data: BEDGRAPH
Series
Accession:
GSE256131
ID:
200256131
2.

NextSeq 2000 (Homo sapiens)

Platform
Accession:
GPL30173
ID:
100030173
3.

D1220-10_MOLM14_dnFOS_noDox

Organism:
Homo sapiens
Source name:
MOLM14
Platform:
GPL30173
Series:
GSE241647 GSE256131
Download data: BEDGRAPH
Sample
Accession:
GSM8086195
ID:
308086195
4.

D1220-9_MOLM14_dnFOS_plusDox

Organism:
Homo sapiens
Source name:
MOLM14
Platform:
GPL30173
Series:
GSE241647 GSE256131
Download data: BEDGRAPH
Sample
Accession:
GSM8086194
ID:
308086194
5.

D1220-8_MOLM14_EV_noDox

Organism:
Homo sapiens
Source name:
MOLM14
Platform:
GPL30173
Series:
GSE241647 GSE256131
Download data: BEDGRAPH
Sample
Accession:
GSM8086193
ID:
308086193
6.

D1220-7_MOLM14_EV_plusDox

Organism:
Homo sapiens
Source name:
MOLM14
Platform:
GPL30173
Series:
GSE241647 GSE256131
Download data: BEDGRAPH
Sample
Accession:
GSM8086192
ID:
308086192
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Supplemental Content

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