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Items: 18

1.

Reorganization of the host epigenome by a viral oncogene

(Submitter supplied) Adenovirus small e1a causes ~70% reduction in cellular levels of histone H3 lysine 18 acetylation (H3K18ac). It is unclear, however, where this dramatic reduction occurs genome-wide. ChIP-seq revealed that e1a erases 95% of H3K18ac peaks in normal fibroblasts and replaces them with one-third as many at new genomic locations. H3K18ac at promoters and intergenic regions of genes with fibroblast-related functions are relocalized after infection to promoters of highly-induced genes that regulate cell cycling and to new putative enhancers. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL10999 GPL11154
15 Samples
Download data: BED, TXT, WIG
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

Illumina Genome Analyzer IIx (Homo sapiens)

Platform
Accession:
GPL10999
ID:
100010999
4.

e1a H3K4me1 ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL11154
Series:
GSE32340
Download data: BED, WIG
Sample
Accession:
GSM873694
ID:
300873694
5.

e1a-infected input control Hiseq_ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL11154
Series:
GSE32340
Download data: BED
Sample
Accession:
GSM802410
ID:
300802410
6.

mock-infected input Hiseq_ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL11154
Series:
GSE32340
Download data: BED
Sample
Accession:
GSM802408
ID:
300802408
7.

mock-infected p107_ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL11154
Series:
GSE32340
Download data: BED, WIG
Sample
Accession:
GSM802404
ID:
300802404
8.

e1a H3K9ac_ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL11154
Series:
GSE32340
Download data: BED, WIG
Sample
Accession:
GSM802402
ID:
300802402
9.

e1a H3K18ac_ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL11154
Series:
GSE32340
Download data: BED, WIG
Sample
Accession:
GSM802400
ID:
300802400
10.

Mock H3K18ac_ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL11154
Series:
GSE32340
Download data: BED, WIG
Sample
Accession:
GSM802399
ID:
300802399
11.

e1a-infected mRNA sequencing

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL10999
Series:
GSE32340
Download data: BED, WIG
Sample
Accession:
GSM802412
ID:
300802412
12.

Mock mRNA control sequencing

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL10999
Series:
GSE32340
Download data: BED, WIG
Sample
Accession:
GSM802411
ID:
300802411
13.

e1a_infected input GAIIx _ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL10999
Series:
GSE32340
Download data: BED
Sample
Accession:
GSM802409
ID:
300802409
14.

mock-infected input GAIIx DSG_ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL10999
Series:
GSE32340
Download data: BED
Sample
Accession:
GSM802407
ID:
300802407
15.

mock-infected input GAIIx_ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL10999
Series:
GSE32340
Download data: BED
Sample
Accession:
GSM802406
ID:
300802406
16.

mock-infected p130_ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL10999
Series:
GSE32340
Download data: BED, WIG
Sample
Accession:
GSM802405
ID:
300802405
17.

mock-infected RB1_ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL10999
Series:
GSE32340
Download data: BED, WIG
Sample
Accession:
GSM802403
ID:
300802403
18.

Mock H3K9ac_ChIP-seq

Organism:
Homo sapiens
Source name:
lung fibroblasts
Platform:
GPL10999
Series:
GSE32340
Download data: BED, WIG
Sample
Accession:
GSM802401
ID:
300802401
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Supplemental Content

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