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Items: 6

1.

Oncogenic BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration [HT-seq]

(Submitter supplied) Most cancer genomics papers to date have focused on aberrations in genomic DNA and protein-coding transcripts. However, around 50% of transcripts have no coding potential and may exist as non-coding RNA. We performed RNA-seq in BRAFv600e melanoma skin cancer and on melanocytes over-expressing oncogenic BRAF to catalog transcriptome remodeling. We discovered that BRAF regulates expression of 1027 protein coding transcripts, 39 annotated lncRNAs and 70 novel transcripts. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platform:
GPL11154
4 Samples
Download data: BW, GTF
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

mm4

Organism:
Homo sapiens
Source name:
primary melanoma #2
Platform:
GPL11154
Series:
GSE33092 GSE37169
Download data: BW
Sample
Accession:
GSM819492
ID:
300819492
4.

mm2

Organism:
Homo sapiens
Source name:
primary melanoma #1
Platform:
GPL11154
Series:
GSE33092 GSE37169
Download data: BW
Sample
Accession:
GSM819491
ID:
300819491
5.

MC_BRAF

Organism:
Homo sapiens
Source name:
Melanocytes + BRAFv600e
Platform:
GPL11154
Series:
GSE33092 GSE37169
Download data: BW, GTF
Sample
Accession:
GSM819490
ID:
300819490
6.

MC_RFP

Organism:
Homo sapiens
Source name:
Melanocytes + RFP (Control)
Platform:
GPL11154
Series:
GSE33092 GSE37169
Download data: BW
Sample
Accession:
GSM819489
ID:
300819489
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Supplemental Content

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