GSE33632[Accession] - GEO DataSets - NCBI

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Items: 17

Select item 2000336321.

Genome-wide analysis of histone eviction by FAIRE-Seq

(Submitter supplied) A major class of chemotherapeutics targets topoisomerase II for DNA double-strand breaks and cancer cell elimination. We compare four members of this class?the anthracyclines doxorubicin, daunorubicin and aclarubicin that does not induce DNA breaks?and a different compound, etoposide. We define a novel activity for anthracyclines: histone eviction from open chromosomal areas. Since histone variant H2AX is also evicted, DNA damage response is attenuated when compared to etoposide. more...

Organism:: Homo sapiens; Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL10999 GPL11154 GPL13112
13 Samples

Download data: BAM, BED

Series

Accession:: GSE33632

ID:: 200033632

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000131122.

Illumina HiSeq 2000 (Mus musculus)

Organism:: Mus musculus

8223 Series
187245 Samples

Platform

Accession:: GPL13112

ID:: 100013112

Select item 1000111543.

Illumina HiSeq 2000 (Homo sapiens)

Organism:: Homo sapiens

10398 Series
180072 Samples

Platform

Accession:: GPL11154

ID:: 100011154

Select item 1000109994.

Illumina Genome Analyzer IIx (Homo sapiens)

Organism:: Homo sapiens

1096 Series
9927 Samples

Platform

Accession:: GPL10999

ID:: 100010999

Select item 3008318705.

MelJuSo etoposide FAIRE-seq

Organism:: Homo sapiens

Source name:: MelJuSo cells

Platform:: GPL10999
Series:: GSE33632 GSE33634

Download data: BAM, BED

Sample

Accession:: GSM831870

ID:: 300831870

SRA Run Selector

Select item 3008318696.

MelJuSo doxorubicin FAIRE-seq

Organism:: Homo sapiens

Source name:: MelJuSo cells

Platform:: GPL10999
Series:: GSE33632 GSE33634

Download data: BAM, BED

Sample

Accession:: GSM831869

ID:: 300831869

SRA Run Selector

Select item 3008318687.

MelJuSo aclarubicin FAIRE-seq

Organism:: Homo sapiens

Source name:: MelJuSo cells

Platform:: GPL10999
Series:: GSE33632 GSE33634

Download data: BAM, BED

Sample

Accession:: GSM831868

ID:: 300831868

SRA Run Selector

Select item 3008318678.

MelJuSo un-treated FAIRE-seq

Organism:: Homo sapiens

Source name:: MelJuSo cells

Platform:: GPL10999
Series:: GSE33632 GSE33634

Download data: BAM, BED

Sample

Accession:: GSM831867

ID:: 300831867

SRA Run Selector

Select item 3011203009.

AML daunorubicin FAIRE-Seq

Organism:: Homo sapiens

Source name:: AML blasts, 90 mg of daunorubicin

Platform:: GPL11154
Series:: GSE33632

Download data: BED

Sample

Accession:: GSM1120300

ID:: 301120300

SRA Run Selector

Select item 30112029910.

AML un-treated FAIRE-Seq

Organism:: Homo sapiens

Source name:: AML blasts, untreated

Platform:: GPL11154
Series:: GSE33632

Download data: BED

Sample

Accession:: GSM1120299

ID:: 301120299

SRA Run Selector

Select item 30095307711.

Mouse heart etoposide FAIRE-seq

Organism:: Mus musculus

Source name:: mouse heart

Platform:: GPL13112
Series:: GSE33632 GSE33634

Download data: BED

Sample

Accession:: GSM953077

ID:: 300953077

SRA Run Selector

Select item 30095307612.

Mouse heart doxorubicin FAIRE-seq

Organism:: Mus musculus

Source name:: mouse heart

Platform:: GPL13112
Series:: GSE33632 GSE33634

Download data: BED

Sample

Accession:: GSM953076

ID:: 300953076

SRA Run Selector

Select item 30095307513.

Mouse heart un-treated FAIRE-seq

Organism:: Mus musculus

Source name:: mouse heart

Platform:: GPL13112
Series:: GSE33632 GSE33634

Download data: BED

Sample

Accession:: GSM953075

ID:: 300953075

SRA Run Selector

Select item 30083186314.

SW620 etoposide FAIRE-seq

Organism:: Homo sapiens

Source name:: SW620 cells

Platform:: GPL11154
Series:: GSE33632 GSE33634

Download data: BAM, BED

Sample

Accession:: GSM831863

ID:: 300831863

SRA Run Selector

Select item 30083186215.

SW620 doxorubicin FAIRE-seq

Organism:: Homo sapiens

Source name:: SW620 cells

Platform:: GPL11154
Series:: GSE33632 GSE33634

Download data: BAM, BED

Sample

Accession:: GSM831862

ID:: 300831862

SRA Run Selector

Select item 30083186116.

SW620 aclarubicin FAIRE-seq

Organism:: Homo sapiens

Source name:: SW620 cells

Platform:: GPL11154
Series:: GSE33632 GSE33634

Download data: BAM, BED

Sample

Accession:: GSM831861

ID:: 300831861

SRA Run Selector

Select item 30083186017.

SW620 un-treated FAIRE-seq

Organism:: Homo sapiens

Source name:: SW620 cells

Platform:: GPL11154
Series:: GSE33632 GSE33634

Download data: BAM, BED

Sample

Accession:: GSM831860

ID:: 300831860

SRA Run Selector

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