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Items: 7

1.

Genome-wide Detection of Genes Targeted by Aberrant Somatic Hypermutation in Lymphoma

(Submitter supplied) We report a novel approach to identify genome-wide somatic hypermutation hotspots from short Illumina H3K4me3 ChIPseq reads in diffuse large B-cell lymphoma cells (DLBCL). Abberant somatic hypermation are known to occur at the promoters of several proto-oncogenes in DLBCL. To identify such events genome-wide, we performed H3K4me3 ChIPseq experiments (as to enrich promoter sequences of actively transcribed genes) in 2 DLBCL cells lines (OCI-Ly1 and OCI-Ly8) and their normal B-cell counterparts, Naive B cells (NBC) and Germinal Center B cells (GCBs). more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL10999 GPL11154
4 Samples
Download data: TXT
Series
Accession:
GSE34316
ID:
200034316
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

Illumina Genome Analyzer IIx (Homo sapiens)

Platform
Accession:
GPL10999
ID:
100010999
4.

OCI-Ly8-H3K4me3-ChIPseq

Organism:
Homo sapiens
Source name:
Diffuse Large B-cell Lymophoma
Platform:
GPL11154
Series:
GSE34316
Download data: TXT
Sample
Accession:
GSM847243
ID:
300847243
5.

GCB-H3K4me3-ChIPseq

Organism:
Homo sapiens
Source name:
Human tonsilar germinal center B cells
Platform:
GPL10999
Series:
GSE34316
Download data: TXT
Sample
Accession:
GSM847245
ID:
300847245
6.

NBC-H3K4me3-ChIPseq

Organism:
Homo sapiens
Source name:
Human tonsilar naïve B cells
Platform:
GPL10999
Series:
GSE34316
Download data: TXT
Sample
Accession:
GSM847244
ID:
300847244
7.

OCI-Ly1-H3K4me3-ChIPseq

Organism:
Homo sapiens
Source name:
Diffuse Large B-cell Lymophoma
Platform:
GPL10999
Series:
GSE34316
Download data: TXT
Sample
Accession:
GSM847242
ID:
300847242
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Supplemental Content

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