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Items: 12

1.

Hes6 expression is controlled by c-Myc and the AR to promote E2F1 activity and poor outcome in castrate-resistant prostate cancer (xenografts)

(Submitter supplied) Hes6 is a transcription co-factor that is associated with stem cell characteristics in neural tissue, but its role in cancer remains uncertain. Here we show that Hes6 is controlled by c-Myc and the AR and can drive castration resistance in xenografts of the androgen-dependent LNCaP prostate cancer cell line model. Hes6 activates a cell cycle enhancing transcriptional network that maintains tumour growth in the absence of circulating androgen but with maintained nuclear AR. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
10 Samples
Download data: TXT
Series
Accession:
GSE36433
ID:
200036433

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Illumina HumanHT-12 V4.0 expression beadchip

(Submitter supplied) The HumanHT-12 v4 Expression BeadChip provides high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments. The updated content on the HumanHT-12 v4 Expression BeadChips provides more biologically meaningful results through genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. more...
Organism:
Homo sapiens
51 DataSets
2929 Series
4 Related Platforms
104243 Samples
Download data: TXT
Platform
Accession:
GPL10558
ID:
100010558

3.

Control_Castrated OWJ5

Organism:
Homo sapiens
Source name:
LNCaP-LM xenograft control
Platform:
GPL10558
Series:
GSE36433 GSE36526
Download data
Sample
Accession:
GSM893322
ID:
300893322

4.

Control_Castrated OWJ2

Organism:
Homo sapiens
Source name:
LNCaP-LM xenograft control
Platform:
GPL10558
Series:
GSE36433 GSE36526
Download data
Sample
Accession:
GSM893321
ID:
300893321

5.

Control_Castrated OWJ75

Organism:
Homo sapiens
Source name:
LNCaP-LM xenograft control
Platform:
GPL10558
Series:
GSE36433 GSE36526
Download data
Sample
Accession:
GSM893320
ID:
300893320

6.

Control_Castrated OWJ59

Organism:
Homo sapiens
Source name:
LNCaP-LM xenograft control
Platform:
GPL10558
Series:
GSE36433 GSE36526
Download data
Sample
Accession:
GSM893319
ID:
300893319

7.

Control_Castrated OWJ52

Organism:
Homo sapiens
Source name:
LNCaP-LM xenograft control
Platform:
GPL10558
Series:
GSE36433 GSE36526
Download data
Sample
Accession:
GSM893318
ID:
300893318

8.

Hes6_Castrated OWJ72

Organism:
Homo sapiens
Source name:
LNCaP-LM xenograft with Hes6 overexpression
Platform:
GPL10558
Series:
GSE36433 GSE36526
Download data
Sample
Accession:
GSM893317
ID:
300893317

9.

Hes6_Castrated OWJ42

Organism:
Homo sapiens
Source name:
LNCaP-LM xenograft with Hes6 overexpression
Platform:
GPL10558
Series:
GSE36433 GSE36526
Download data
Sample
Accession:
GSM893316
ID:
300893316

10.

Hes6_Castrated OWJ40

Organism:
Homo sapiens
Source name:
LNCaP-LM xenograft with Hes6 overexpression
Platform:
GPL10558
Series:
GSE36433 GSE36526
Download data
Sample
Accession:
GSM893315
ID:
300893315

11.

Hes6_Castrated OWJ39

Organism:
Homo sapiens
Source name:
LNCaP-LM xenograft with Hes6 overexpression
Platform:
GPL10558
Series:
GSE36433 GSE36526
Download data
Sample
Accession:
GSM893314
ID:
300893314

12.

Hes6_Castrated OWJ64

Organism:
Homo sapiens
Source name:
LNCaP-LM xenograft with Hes6 overexpression
Platform:
GPL10558
Series:
GSE36433 GSE36526
Download data
Sample
Accession:
GSM893313
ID:
300893313

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