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Items: 9

1.

Identification of direct targets and modified bases of RNA cytosine methyltransferases

(Submitter supplied) We report development of a mechanism-based technique, Aza-IP, that utilizes the stable covalent linkage formed in vivo between an RNA methyltransferase (m5C-RMT) and 5-azacytidine (5-aza-C) incorporated within the target RNA to enable specific target enrichment, coupled with high-throughput sequencing to provide target identification. We apply Aza-IP to two enzyme types, DNMT2 and NSUN2, the latter with important roles in fertility, intellectual ability, stem cells and cancer. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL11154
7 Samples
Download data: XLS
Series
Accession:
GSE38957
ID:
200038957

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10400 Series
180082 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

NSUN2-Aza-IP (IgG-Control)

Organism:
Homo sapiens
Source name:
HeLa_NSUN2-Aza-IfG control
Platform:
GPL11154
Series:
GSE38957
Download data
Sample
Accession:
GSM1083885
ID:
301083885

SRA Run Selector

4.

NSUN2-Aza-IP (anti-V5-Rep2)

Organism:
Homo sapiens
Source name:
HeLa_NSUN2-Aza-antiV5_IP
Platform:
GPL11154
Series:
GSE38957
Download data
Sample
Accession:
GSM1083884
ID:
301083884

SRA Run Selector

5.

NSUN2-Aza-IP (anti-V5-Rep1)

Organism:
Homo sapiens
Source name:
HeLa_NSUN2-Aza-antiV5_IP
Platform:
GPL11154
Series:
GSE38957
Download data
Sample
Accession:
GSM1083883
ID:
301083883

SRA Run Selector

6.

DsRed-Aza-Input-mRNA

Organism:
Homo sapiens
Source name:
HeLa cells
Platform:
GPL11154
Series:
GSE38957
Download data
Sample
Accession:
GSM952755
ID:
300952755

SRA Run Selector

7.

DNMT2-Aza-Input-mRNA

Organism:
Homo sapiens
Source name:
HeLa cells
Platform:
GPL11154
Series:
GSE38957
Download data
Sample
Accession:
GSM952754
ID:
300952754

SRA Run Selector

8.

DsRed-Aza-IP

Organism:
Homo sapiens
Source name:
HeLa cells
Platform:
GPL11154
Series:
GSE38957
Download data
Sample
Accession:
GSM952753
ID:
300952753

SRA Run Selector

9.

DNMT2-Aza-IP

Organism:
Homo sapiens
Source name:
HeLa cells
Platform:
GPL11154
Series:
GSE38957
Download data
Sample
Accession:
GSM952752
ID:
300952752

SRA Run Selector

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