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Items: 7

1.

DGCR8 HITS-CLIP reveals novel functions for the Microprocessor (CLIP-seq)

(Submitter supplied) The Drosha-DGCR8 complex (Microprocessor) is required for microRNA (miRNA) biogenesis. DGCR8 contains two double-stranded RNA binding motifs that recognize the RNA substrate, whereas Drosha functions as the endonuclease. We have used high-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP) to identify endogenous RNA targets of DGCR8 in mammalian cells. Unexpectedly, miRNAs were not the most abundant targets. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL10999 GPL11154
4 Samples
Download data: BEDGRAPH
Series
Accession:
GSE39086
ID:
200039086
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

Illumina Genome Analyzer IIx (Homo sapiens)

Platform
Accession:
GPL10999
ID:
100010999
4.

T7.1 (overexpressed DGCR8 IP)

Organism:
Homo sapiens
Source name:
HEK293T
Platform:
GPL10999
Series:
GSE39086
Download data: BEDGRAPH
Sample
Accession:
GSM955511
ID:
300955511
5.

D8.1 (endogenous DGCR8 IP)

Organism:
Homo sapiens
Source name:
HEK293T
Platform:
GPL10999
Series:
GSE39086
Download data: BEDGRAPH
Sample
Accession:
GSM955510
ID:
300955510
6.

T7.2 (overexpressed DGCR8 IP)

Organism:
Homo sapiens
Source name:
HEK293T
Platform:
GPL11154
Series:
GSE39086
Download data: BEDGRAPH
Sample
Accession:
GSM955513
ID:
300955513
7.

D8.2 (endogenous DGCR8 IP)

Organism:
Homo sapiens
Source name:
HEK293T
Platform:
GPL11154
Series:
GSE39086
Download data: BEDGRAPH
Sample
Accession:
GSM955512
ID:
300955512
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Supplemental Content

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