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Items: 8

1.

Histone acetylation regulates intracellular pH

(Submitter supplied) Differences in global levels of histone acetylation occur in normal and cancer cells, although the reason cells regulate these levels has remained unclear. Here we demonstrate a role for histone acetylation in regulating intracellular pH (pHi). As pHi decreases, histones are globally deacetylated by histone deacetylases (HDACs) and the released acetate anions are co-exported with protons out of the cell by monocarboxylate transporters (MCTs), preventing further reductions in pHi. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
6 Samples
Download data: BED, TXT, WIG
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

mRNA 3mM sodium bicarbonate

Organism:
Homo sapiens
Source name:
mRNA 3mM sodium bicarbonate
Platform:
GPL11154
Series:
GSE40114
Download data: BED
Sample
Accession:
GSM985139
ID:
300985139
4.

mRNA 25mM sodium bicarbonate

Organism:
Homo sapiens
Source name:
mRNA 25mM sodium bicarbonate
Platform:
GPL11154
Series:
GSE40114
Download data: BED
Sample
Accession:
GSM985138
ID:
300985138
5.

WCE 3mM sodium bicarbonate

Organism:
Homo sapiens
Source name:
WCE 3mM sodium bicarbonate
Platform:
GPL11154
Series:
GSE40114
Download data: BED
Sample
Accession:
GSM985137
ID:
300985137
6.

WCE 25mM sodium bicarbonate

Organism:
Homo sapiens
Source name:
WCE 25mM sodium bicarbonate
Platform:
GPL11154
Series:
GSE40114
Download data: BED
Sample
Accession:
GSM985136
ID:
300985136
7.

H4K16ac 3mM sodium bicarbonate

Organism:
Homo sapiens
Source name:
H4K16ac 3mM sodium bicarbonate
Platform:
GPL11154
Series:
GSE40114
Download data: BED, WIG
Sample
Accession:
GSM985135
ID:
300985135
8.

H4K16ac 25mM sodium bicarbonate

Organism:
Homo sapiens
Source name:
H4K16ac 25mM sodium bicarbonate
Platform:
GPL11154
Series:
GSE40114
Download data: BED, WIG
Sample
Accession:
GSM985134
ID:
300985134
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Supplemental Content

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