GSE40665[Accession] - GEO DataSets - NCBI

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Items: 12

Select item 2000406651.

Integrative Analyses of Gene Expression and DNA Methylation Profiles in a Breast Cancer Cell Line Model of Tamoxifen-Resistance Indicate a Crucial Role of Cells with Stem-like Properties

(Submitter supplied) Purpose: Development of resistance to tamoxifen is an important clinical issue in the treatment of patients with breast cancer. Tamoxifen resistance may be the result of the acquisition of epigenetic regulation such as DNA methylation within breast cancer cells resulting in changed mRNA expression of genes being pivotal for estrogen dependent growth. Alternatively, tamoxifen resistance may be due to selection of preexisting resistant cells, which may exhibit cancer stem-like characteristics or a combination of the two mechanisms. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platform:: GPL11154
10 Samples

Download data: TXT

Series

Accession:: GSE40665

ID:: 200040665

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000111542.

Illumina HiSeq 2000 (Homo sapiens)

Organism:: Homo sapiens

10400 Series
180082 Samples

Platform

Accession:: GPL11154

ID:: 100011154

Select item 3009989673.

TMAR 8-MMSDK analysis

Organism:: Homo sapiens

Source name:: Breast cancer cell line

Platform:: GPL11154
Series:: GSE40665

Sample

Accession:: GSM998967

ID:: 300998967

SRA Run Selector

Select item 3009989664.

TMAR 7-MMSDK analysis

Organism:: Homo sapiens

Source name:: Breast cancer cell line

Platform:: GPL11154
Series:: GSE40665

Sample

Accession:: GSM998966

ID:: 300998966

SRA Run Selector

Select item 3009989655.

TMAR 4-MMSDK analysis

Organism:: Homo sapiens

Source name:: Breast cancer cell line

Platform:: GPL11154
Series:: GSE40665

Sample

Accession:: GSM998965

ID:: 300998965

SRA Run Selector

Select item 3009989646.

TMAR 1-MMSDK analysis

Organism:: Homo sapiens

Source name:: Breast cancer cell line

Platform:: GPL11154
Series:: GSE40665

Sample

Accession:: GSM998964

ID:: 300998964

SRA Run Selector

Select item 3009989637.

MCF-7/S0.5-MMSDK analysis

Organism:: Homo sapiens

Source name:: Breast cancer cell line

Platform:: GPL11154
Series:: GSE40665

Sample

Accession:: GSM998963

ID:: 300998963

SRA Run Selector

Select item 3009989628.

TMAR 8-DGE analysis

Organism:: Homo sapiens

Source name:: Breast cancer cell line

Platform:: GPL11154
Series:: GSE40665

Sample

Accession:: GSM998962

ID:: 300998962

SRA Run Selector

Select item 3009989619.

TMAR 7-DGE analysis

Organism:: Homo sapiens

Source name:: Breast cancer cell line

Platform:: GPL11154
Series:: GSE40665

Sample

Accession:: GSM998961

ID:: 300998961

SRA Run Selector

Select item 30099896010.

TMAR 4-DGE analysis

Organism:: Homo sapiens

Source name:: Breast cancer cell line

Platform:: GPL11154
Series:: GSE40665

Sample

Accession:: GSM998960

ID:: 300998960

SRA Run Selector

Select item 30099895911.

TMAR 1-DGE analysis

Organism:: Homo sapiens

Source name:: Breast cancer cell line

Platform:: GPL11154
Series:: GSE40665

Sample

Accession:: GSM998959

ID:: 300998959

SRA Run Selector

Select item 30099895812.

MCF-7/S0.5-DGE analysis

Organism:: Homo sapiens

Source name:: Breast cancer cell line

Platform:: GPL11154
Series:: GSE40665

Sample

Accession:: GSM998958

ID:: 300998958

SRA Run Selector

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GSE40665[Accession] (12)
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