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Items: 4

1.

Integrated detection of both 5-mC and 5-hmC by high-throughput tag sequencing technology highlights methylation reprogramming of bivalent genes during cellular differentiation [MeDIP_hMeDIP]

(Submitter supplied) 5-methylcytosine (5-mC) can be oxidized to 5-hydroxymethylcytosine (5-hmC). Genome-wide profiling of 5-hmC thus far indicated 5-hmC may not only be an intermediate form of DNA demethylation but could also constitute an epigenetic mark per se. We describe a cost-effective and selective method to detect both the hydroxymethylation and methylation status of cytosines in more than 1.8 million MspI sites in the human genome. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL11154
2 Samples
Download data: WIG
Series
Accession:
GSE41070
ID:
200041070
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

H9_hmedip

Organism:
Homo sapiens
Source name:
embryonic stem cells
Platform:
GPL11154
Series:
GSE41070 GSE41071
Download data: WIG
Sample
Accession:
GSM1008199
ID:
301008199
4.

H9_medip

Organism:
Homo sapiens
Source name:
embryonic stem cells
Platform:
GPL11154
Series:
GSE41070 GSE41071
Download data: WIG
Sample
Accession:
GSM1008198
ID:
301008198
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Supplemental Content

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