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Items: 13

1.

Signaling Pathways Deferentially Affect RNA Polymerase II Initiation, Pausing, and Elongation in Human Cells: Estrogen dependent signaling in MCF-7 cells

(Submitter supplied) We used Global Run-on and Sequencing (GRO-seq) to measure the rate of transcription elongation by RNA polymerase II (Pol II) following gene activation. We observed that Pol II elongation rates can vary as much as 4-fold at different genomic loci and in response to two distinct cellular signaling pathways (i.e., estrogen and TNFα). Elongation rates are slowest near the promoter and increase during the first ~15 kb transcribed into the gene body. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
11 Samples
Download data: BED, TSV, TXT
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

GRO-seq_E2_40m_MCF7_3

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL11154
Series:
GSE41324
Download data: BED
Sample
Accession:
GSM1014647
ID:
301014647
4.

GRO-seq_E2_40m_MCF7_2

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL11154
Series:
GSE41324
Download data: BED
Sample
Accession:
GSM1014646
ID:
301014646
5.

GRO-seq_E2_40m_MCF7_1

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL11154
Series:
GSE41324
Download data: BED
Sample
Accession:
GSM1014645
ID:
301014645
6.

GRO-seq_E2_25m_MCF7_2

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL11154
Series:
GSE41324
Download data: BED
Sample
Accession:
GSM1014644
ID:
301014644
7.

GRO-seq_E2_25m_MCF7_1

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL11154
Series:
GSE41324
Download data: BED
Sample
Accession:
GSM1014643
ID:
301014643
8.

GRO-seq_E2_10m_MCF7_3

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL11154
Series:
GSE41324
Download data: BED
Sample
Accession:
GSM1014642
ID:
301014642
9.

GRO-seq_E2_10m_MCF7_2

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL11154
Series:
GSE41324
Download data: BED
Sample
Accession:
GSM1014641
ID:
301014641
10.

GRO-seq_E2_10m_MCF7_1

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL11154
Series:
GSE41324
Download data: BED
Sample
Accession:
GSM1014640
ID:
301014640
11.

GRO-seq_Vehicle_MCF7_3

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL11154
Series:
GSE41324
Download data: BED
Sample
Accession:
GSM1014639
ID:
301014639
12.

GRO-seq_Vehicle_MCF7_2

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL11154
Series:
GSE41324
Download data: BED
Sample
Accession:
GSM1014638
ID:
301014638
13.

GRO-seq_Vehicle_MCF7_1

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL11154
Series:
GSE41324
Download data: BED
Sample
Accession:
GSM1014637
ID:
301014637
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Supplemental Content

db=gds|term=GSE41324[Accession]|query=1|qty=2|blobid=MCID_6642c3115f31ac491175f11c|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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