GSE42075[Accession] - GEO DataSets - NCBI

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Items: 4

Select item 2000420751.

RUNX1 is a key target gene in t(4;11) leukemias and contributes to gene activation by interacting with the AF4-MLL complex

(Submitter supplied) The Mixed Lineage Leukemia 1 protein (MLL1) is an important epigenetic regulator required for the maintenance of gene activation during development. MLL1 chromosome translocations produce novel fusion proteins that cause aggressive leukemias in humans. Individual MLL1 fusion proteins have distinct leukemic phenotypes even when expressed in the same cell type, but how this distinction is delineated on a molecular level is poorly understood. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11154
2 Samples

Download data: BIGBED, BIGWIG

Series

Accession:: GSE42075

ID:: 200042075

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000111542.

Illumina HiSeq 2000 (Homo sapiens)

Organism:: Homo sapiens

10400 Series
180082 Samples

Platform

Accession:: GPL11154

ID:: 100011154

Select item 3010320763.

input_RUNX1_ChIPSeq

Organism:: Homo sapiens

Source name:: Acute lymphoblastic leukemia cells with MLL/AF4 translocation

Platform:: GPL11154
Series:: GSE42075

Download data: BIGWIG

Sample

Accession:: GSM1032076

ID:: 301032076

SRA Run Selector

Select item 3010320754.

Organism:: Homo sapiens

Source name:: Acute lymphoblastic leukemia cells with MLL/AF4 translocation

Platform:: GPL11154
Series:: GSE42075

Download data: BIGBED, BIGWIG

Sample

Accession:: GSM1032075

ID:: 301032075

SRA Run Selector

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GSE42075[Accession] (4)
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