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Items: 5

1.

Direct ChIP-bisulfite sequencing reveals a role of H3K27me3 mediating aberrant hypermethylation of promoter CpG islands in cancer cells (RNA-seq)

(Submitter supplied) Aberrant DNA hypermethylation of CpG island (CGI) promoters are associated with transcriptional repression of many tumor suppressor genes and lead to tumor progression in many cancers. Most recently, one research group observed that aberrantly hypermethylated genes in multiple cancers are already repressed, but their promoters are maintained in a hypomethylated state in pre-cancerous tissues.Their studies didn't provide a clue to explain by what mechanisms those genes were repressed in pre-cancerous tissues. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
3 Samples
Download data: BED, TXT
Series
Accession:
GSE43093
ID:
200043093
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

BGC-823-RNA-seq

Organism:
Homo sapiens
Source name:
gastric adenocarcinoma cells
Platform:
GPL11154
Series:
GSE43093 GSE43096
Download data: BED, TXT
Sample
Accession:
GSM1056529
ID:
301056529
4.

AGS-RNA-seq

Organism:
Homo sapiens
Source name:
gastric adenocarcinoma cells
Platform:
GPL11154
Series:
GSE43093 GSE43096
Download data: BED, TXT
Sample
Accession:
GSM1056528
ID:
301056528
5.

YH-RNA-seq

Organism:
Homo sapiens
Source name:
lymphoblastoid cells
Platform:
GPL11154
Series:
GSE43093 GSE43096
Download data: BED, TXT
Sample
Accession:
GSM1056527
ID:
301056527
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Supplemental Content

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