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Items: 1 to 20 of 21

1.

Molecular characterization of t(2;14)(q22;q32) and t(6;14)(q25;q32) translocations in mixed myeloid/T lymphoid leukemia patients.

(Submitter supplied) We characterized two recurrent translocations, i.e. t(2;14)(q22.3;q32) and t(6;14)(q25;q32), in FLT3 positive mixed myeloid/T-cell lymphoid leukemias (MLPA). Both translocations involved BCL11B at 14q32. In cases with t(2;14), the 2q22.3 breakpoint disrupted ZEB2 and produced a ZEB2-BCL11B fusion, a significant ZEB2-BCL11B over-expression with concomitant BCL11B wild type (wt) down-regulation. In cases with t(6;14), the 6q25 breakpoints fell in a 100Kb region where no genes have been mapped thus it not appeared to produce a fusion transcript. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
19 Samples
Download data: TXT
Series
Accession:
GSE43417
ID:
200043417
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

PML-RARa/FLT3+_50195

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062251
ID:
301062251
4.

PML-RARa/FLT3+_50536

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062250
ID:
301062250
5.

PML-RARa/FLT3+_45095

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062249
ID:
301062249
6.

PML-RARa/FLT3+_50569

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062248
ID:
301062248
7.

NPM1+/FLT3-_49532

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062247
ID:
301062247
8.

NPM1+/FLT3-_48899

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062246
ID:
301062246
9.

NPM1+/FLT3-_48865

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062245
ID:
301062245
10.

NPM1+/FLT3-_49213

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062244
ID:
301062244
11.

NPM1+/FLT3-_48882

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062243
ID:
301062243
12.

NPM1+/FLT3+_49305

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062242
ID:
301062242
13.

NPM1+/FLT3+_48604

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062241
ID:
301062241
14.

NPM1+/FLT3+_49666

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062240
ID:
301062240
15.

NPM1+/FLT3+_48792

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062239
ID:
301062239
16.

NPM1+/FLT3+_48758

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062238
ID:
301062238
17.

t(6;14)_390_11_pt.7

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062237
ID:
301062237
18.

t(2;14)_176_10_pt.5

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062236
ID:
301062236
19.

t(2;14)_709_05_pt.4

Organism:
Homo sapiens
Source name:
Bone Marrow
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062235
ID:
301062235
20.

t(2;14)_81-07 _pt.2

Organism:
Homo sapiens
Source name:
Peripheral Blood
Platform:
GPL11154
Series:
GSE43417
Download data
Sample
Accession:
GSM1062234
ID:
301062234
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