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Items: 8

1.

Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap

(Submitter supplied) Recent genome wide association studies have identified a number of genes that contribute to the risk for coronary heart disease. One such gene, TCF21, encodes a basic-helix-loop-helix transcription factor believed to serve a critical role in the development of epicardial progenitor cells that give rise to coronary artery smooth muscle cells (SMC) and cardiac fibroblasts. Using reporter gene and immunolocalization studies with mouse and human tissues we have found that vascular TCF21 expression in the adult is restricted primarily to adventitial cells associated with coronary arteries and also medial SMC in the proximal aorta of mouse. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
6 Samples
Download data: BED
Series
Accession:
GSE44461
ID:
200044461

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10400 Series
180082 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

TCF21 knockdown siRNA technical replicate 3

Organism:
Homo sapiens
Source name:
in vitro cultured primary coronary artery smooth muscle cells
Platform:
GPL11154
Series:
GSE44461
Download data: BED
Sample
Accession:
GSM1085741
ID:
301085741

SRA Run Selector

4.

TCF21 knockdown siRNA technical replicate 2

Organism:
Homo sapiens
Source name:
in vitro cultured primary coronary artery smooth muscle cells
Platform:
GPL11154
Series:
GSE44461
Download data: BED
Sample
Accession:
GSM1085740
ID:
301085740

SRA Run Selector

5.

TCF21 knockdown siRNA technical replicate 1

Organism:
Homo sapiens
Source name:
in vitro cultured primary coronary artery smooth muscle cells
Platform:
GPL11154
Series:
GSE44461
Download data: BED
Sample
Accession:
GSM1085739
ID:
301085739

SRA Run Selector

6.

non-silencing control siRNA technical replicate 3

Organism:
Homo sapiens
Source name:
in vitro cultured primary coronary artery smooth muscle cells
Platform:
GPL11154
Series:
GSE44461
Download data: BED
Sample
Accession:
GSM1085738
ID:
301085738

SRA Run Selector

7.

non-silencing control siRNA technical replicate 2

Organism:
Homo sapiens
Source name:
in vitro cultured primary coronary artery smooth muscle cells
Platform:
GPL11154
Series:
GSE44461
Download data: BED
Sample
Accession:
GSM1085737
ID:
301085737

SRA Run Selector

8.

non-silencing control siRNA technical replicate 1

Organism:
Homo sapiens
Source name:
in vitro cultured primary coronary artery smooth muscle cells
Platform:
GPL11154
Series:
GSE44461
Download data: BED
Sample
Accession:
GSM1085736
ID:
301085736

SRA Run Selector

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