GSE44568[Accession] - GEO DataSets - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Search results

Items: 8

Select item 2000445681.

Identification of mRNAs bound and regulated by human LIN28 proteins and molecular requirements for RNA recognition [RNA-Seq]

(Submitter supplied) Human LIN28A and B are RNA-binding proteins (RBPs) conserved in animals with important roles during development and stem cell reprogramming. We used Photoactivatable-Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation (PAR-CLIP) in HEK293 cells and identified a largely overlapping set of ~3,000 mRNAs at ~9,500 sites located in the 3’UTR and CDS. In vitro and in vivo, LIN28 preferentially bound single-stranded RNA containing a uridine-rich element and one or more flanking guanosines, and appeared to be able to disrupt base-pairing to access these elements when embedded in predicted secondary structure. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL11154
6 Samples

Download data: TXT

Series

Accession:: GSE44568

ID:: 200044568

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000111542.

Illumina HiSeq 2000 (Homo sapiens)

Organism:: Homo sapiens

10400 Series
180082 Samples

Platform

Accession:: GPL11154

ID:: 100011154

Select item 3010870283.

LIN28B_knockdown_rep2

Organism:: Homo sapiens

Source name:: HEK 293 cells inducibly expressing FLAG/HA tagged LIN28B; transgene not induced; siRNA transfected; replicate 2

Platform:: GPL11154
Series:: GSE44568 GSE44616

Download data: TXT

Sample

Accession:: GSM1087028

ID:: 301087028

SRA Run Selector

Select item 3010870274.

LIN28B_knockdown_rep1

Organism:: Homo sapiens

Source name:: HEK 293 cells inducibly expressing FLAG/HA tagged LIN28B; transgene not induced; siRNA transfected; replicate 1

Platform:: GPL11154
Series:: GSE44568 GSE44616

Download data: TXT

Sample

Accession:: GSM1087027

ID:: 301087027

SRA Run Selector

Select item 3010870265.

LIN28B_induced_rep2

Organism:: Homo sapiens

Source name:: HEK 293 cells expressing FLAG/HA tagged LIN28B; transgene expression induced; mock transfected; replicate 2

Platform:: GPL11154
Series:: GSE44568 GSE44616

Download data: TXT

Sample

Accession:: GSM1087026

ID:: 301087026

SRA Run Selector

Select item 3010870256.

LIN28B_induced_rep1

Organism:: Homo sapiens

Source name:: HEK 293 cells expressing FLAG/HA tagged LIN28B; transgene expression induced; mock transfected; replicate 1

Platform:: GPL11154
Series:: GSE44568 GSE44616

Download data: TXT

Sample

Accession:: GSM1087025

ID:: 301087025

SRA Run Selector

Select item 3010870247.

LIN28B_not_induced_rep2

Organism:: Homo sapiens

Source name:: HEK 293 cells inducibly expressing FLAG/HA tagged LIN28B; transgene expression not induced; mock transfected; replicate 2

Platform:: GPL11154
Series:: GSE44568 GSE44616

Download data: TXT

Sample

Accession:: GSM1087024

ID:: 301087024

SRA Run Selector

Select item 3010870238.

LIN28B_not_induced_rep1

Organism:: Homo sapiens

Source name:: HEK 293 cells inducibly expressing FLAG/HA tagged LIN28B; transgene expression not induced; mock transfected; replicate 1

Platform:: GPL11154
Series:: GSE44568 GSE44616

Download data: TXT

Sample

Accession:: GSM1087023

ID:: 301087023

SRA Run Selector

Supplemental Content

Filters: Manage Filters

Find related data

Search details

Important Links

Recent activity

Clear Turn Off Turn On

GSE44568[Accession] (8)
GEO DataSets

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Genes & Expression > Gene Expression Omnibus (GEO) Datasets