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Items: 8

1.

Genome-wide maps of CENP-A nucleosomes in three neocentromere-containing cell lines

(Submitter supplied) We used native ChIP-seq of CENP-A-containing particles from normal centromeres on alpha-satellite DNA and three naturally-occurring neocentromeres to test the proposed models for the major form of the fundamental repeating unit of centromeric chromatin. We found that the predominant form of the CENP-A particle at the centromere is an octameric nucleosome with loose terminal DNA. Additionally, we found CENP-A nucleosomes are strongly phased on the 171 bp alpha-satellite monomers of normal centromeres, and also display strong positioning and neocentromeres.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
6 Samples
Download data: BEDGRAPH, TXT
Series
Accession:
GSE44724
ID:
200044724
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

Input DNA [MS4221 cell line]

Organism:
Homo sapiens
Source name:
MS4221 cell line
Platform:
GPL11154
Series:
GSE44724
Download data
Sample
Accession:
GSM1089633
ID:
301089633
4.

Input DNA [IMS13q cell line]

Organism:
Homo sapiens
Source name:
IMS13q cell line
Platform:
GPL11154
Series:
GSE44724
Download data
Sample
Accession:
GSM1089632
ID:
301089632
5.

Input DNA [PDNC4 cell line]

Organism:
Homo sapiens
Source name:
PDNC4 cell line
Platform:
GPL11154
Series:
GSE44724
Download data
Sample
Accession:
GSM1089631
ID:
301089631
6.

CENP-A ChIP-seq [MS4221 cell line]

Organism:
Homo sapiens
Source name:
MS4221 cell line
Platform:
GPL11154
Series:
GSE44724
Download data: BEDGRAPH, TXT
Sample
Accession:
GSM1089630
ID:
301089630
7.

CENP-A ChIP-seq [IMS13q cell line]

Organism:
Homo sapiens
Source name:
IMS13q cell line
Platform:
GPL11154
Series:
GSE44724
Download data: BEDGRAPH
Sample
Accession:
GSM1089629
ID:
301089629
8.

CENP-A ChIP-seq [PDNC4 cell line]

Organism:
Homo sapiens
Source name:
PDNC4 cell line
Platform:
GPL11154
Series:
GSE44724
Download data: BEDGRAPH
Sample
Accession:
GSM1089628
ID:
301089628
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Supplemental Content

db=gds|term=GSE44724[Accession]|query=1|qty=2|blobid=MCID_6642eec45f31ac49117b9ecb|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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