U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 23

1.

Tight coordination of protein translation and heat shock factor 1 activation supports the anabolic malignant state [ChIP-Seq]

(Submitter supplied) A unifying characteristic of aggressive cancers is a profound anabolic shift in metabolism to enable sustained proliferation and biomass expansion. The ribosome is centrally situated to sense metabolic states but whether it impacts systems that promote cellular survival is unknown. Here, through integrated chemical-genetic analyses, we find that a dominant transcriptional effect of blocking protein translation in cancer cells is complete inactivation of heat shock factor 1 (HSF1), a multifaceted transcriptional regulator of the heat-shock response and many other cellular processes essential for tumorigenesis. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
21 Samples
Download data: XLSX
Series
Accession:
GSE45852
ID:
200045852

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10400 Series
180082 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

M091_10-uM-CHX_IGG

Organism:
Homo sapiens
Source name:
M0-91 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116673
ID:
301116673

SRA Run Selector

4.

M091_10-uM-CHX_HSF1_R2

Organism:
Homo sapiens
Source name:
M0-91 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116672
ID:
301116672

SRA Run Selector

5.

M091_10-uM-CHX_HSF1_R1

Organism:
Homo sapiens
Source name:
M0-91 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116671
ID:
301116671

SRA Run Selector

6.

M091_100-nM-27A_IGG

Organism:
Homo sapiens
Source name:
M0-91 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116670
ID:
301116670

SRA Run Selector

7.

M091_100-nM-27A_HSF1_R2

Organism:
Homo sapiens
Source name:
M0-91 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116669
ID:
301116669

SRA Run Selector

8.

M091_100-nM-27A_HSF1_R1

Organism:
Homo sapiens
Source name:
M0-91 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116668
ID:
301116668

SRA Run Selector

9.

M091_20-nM-27A_IGG

Organism:
Homo sapiens
Source name:
M0-91 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116667
ID:
301116667

SRA Run Selector

10.

M091_20-nM-27A_HSF1_R2

Organism:
Homo sapiens
Source name:
M0-91 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116666
ID:
301116666

SRA Run Selector

11.

M091_20-nM-27A_HSF1_R1

Organism:
Homo sapiens
Source name:
M0-91 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116665
ID:
301116665

SRA Run Selector

12.

M091_DMSO_IGG

Organism:
Homo sapiens
Source name:
M0-91 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116664
ID:
301116664

SRA Run Selector

13.

M091_DMSO_HSF1

Organism:
Homo sapiens
Source name:
M0-91 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116663
ID:
301116663

SRA Run Selector

14.

MCF7_10-uM-CHX_IGG

Organism:
Homo sapiens
Source name:
MCF7 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116662
ID:
301116662

SRA Run Selector

15.

MCF7_10-uM-CHX_RNAPOLII_R2

Organism:
Homo sapiens
Source name:
MCF7 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116661
ID:
301116661

SRA Run Selector

16.

MCF7_10-uM-CHX_RNAPOLII_R1

Organism:
Homo sapiens
Source name:
MCF7 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116660
ID:
301116660

SRA Run Selector

17.

MCF7_10-uM-CHX_HSF1_R2

Organism:
Homo sapiens
Source name:
MCF7 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116659
ID:
301116659

SRA Run Selector

18.

MCF7_10-uM-CHX_HSF1_R1

Organism:
Homo sapiens
Source name:
MCF7 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116658
ID:
301116658

SRA Run Selector

19.

MCF7_DMSO_IGG

Organism:
Homo sapiens
Source name:
MCF7 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116657
ID:
301116657

SRA Run Selector

20.

MCF7_DMSO_RNAPOLII_R2

Organism:
Homo sapiens
Source name:
MCF7 cells
Platform:
GPL11154
Series:
GSE45852 GSE45853
Download data
Sample
Accession:
GSM1116656
ID:
301116656

SRA Run Selector

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filters: Manage Filters

db=gds|term=GSE45852[Accession]|query=1|qty=2|blobid=MCID_66442f36ec958f7d10218377|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Important Links

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Genes & Expression > Gene Expression Omnibus (GEO) Datasets
Support Center