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Items: 4

1.

Age-related methylation changes are associated with altered transcriptional circuitry [Methyl-seq]

(Submitter supplied) Altered DNA methylation patterns represent an attractive mechanism for the phenotypic changes associated with human aging. Several studies have described age-related methylation changes to various extents, but their functional significance has remained largely unclear. We have now used an integrated methylome and transcriptome sequencing approach to characterize age-related methylation changes in the human epidermis and to analyze their impact on gene expression. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL11154
2 Samples
Download data: BEDGRAPH
Series
Accession:
GSE46450
ID:
200046450
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

Old

Organism:
Homo sapiens
Source name:
skin_old
Platform:
GPL11154
Series:
GSE46450 GSE46487
Download data: BEDGRAPH
Sample
Accession:
GSM1130491
ID:
301130491
4.

Young

Organism:
Homo sapiens
Source name:
skin_young
Platform:
GPL11154
Series:
GSE46450 GSE46487
Download data: BEDGRAPH
Sample
Accession:
GSM1130490
ID:
301130490
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Supplemental Content

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