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Items: 9

1.

MicroRNA Target Site Identification by Integrating Sequence and Binding Information

(Submitter supplied) High-throughput sequencing has opened numerous possibilities for the identification of regulatory RNA-binding events. Cross-linking and immunoprecipitation of Argonaute protein members can pinpoint microRNA target sites within tens of bases, but leaves the identity of the microRNA unresolved. A flexible computational framework that integrates sequence with cross-linking features reliably identifies the microRNA family involved in each binding event, considerably outperforms sequence-only approaches, and quantifies the prevalence of noncanonical binding modes.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL11154 GPL10999
6 Samples
Download data: BED, TXT
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

Illumina Genome Analyzer IIx (Homo sapiens)

Platform
Accession:
GPL10999
ID:
100010999
4.

LCLBACD3

Organism:
Homo sapiens
Source name:
LCL cell line established using EBV B95-8 BACmid lacking ebv-mir-BHRF1-3 (D3)
Platform:
GPL11154
Series:
GSE46611
Download data
Sample
Accession:
GSM1133251
ID:
301133251
5.

LCLBACD2

Organism:
Homo sapiens
Source name:
LCL cell line established using EBV B95-8 BACmid lacking ebv-mir-BHRF1-2 (D2)
Platform:
GPL11154
Series:
GSE46611
Download data
Sample
Accession:
GSM1133250
ID:
301133250
6.

LCLBACD1_2

Organism:
Homo sapiens
Source name:
LCL cell line established using EBV B95-8 BACmid lacking ebv-mir-BHRF1-1 (D1), RNA-seq biological replicate #2
Platform:
GPL11154
Series:
GSE46611
Download data
Sample
Accession:
GSM1133249
ID:
301133249
7.

LCLBACD1_1

Organism:
Homo sapiens
Source name:
LCL cell line established using EBV B95-8 BACmid lacking ebv-mir-BHRF1-1 (D1), RNA-seq biological replicate #1
Platform:
GPL11154
Series:
GSE46611
Download data
Sample
Accession:
GSM1133248
ID:
301133248
8.

LCLBACWT

Organism:
Homo sapiens
Source name:
LCL cell line established using EBV B95-8 BACmid
Platform:
GPL11154
Series:
GSE46611
Download data
Sample
Accession:
GSM1133247
ID:
301133247
9.

Ago2 PAR-CLIP

Organism:
Homo sapiens
Source name:
LCL cell line established using EBV B95-8 BACmid lacking ebv-mir-BHRF1-2 (D2)
Platform:
GPL10999
Series:
GSE46611
Download data: BED
Sample
Accession:
GSM1133252
ID:
301133252
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Supplemental Content

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