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Items: 6

1.

Whole-genome analysis of 5-hydroxymethylcytosines and 5-methylcytosines at base resolution in human brain

(Submitter supplied) 5-hydroxymethylcytosines (5hmC) is particularly abundant in mammalian brain with little-known functions. Here we present the first genome-wide and single-base-resolution maps of 5hmC and 5mC in human brain by combined application of TAB-Seq and MethylC-Seq. We report that the majority of modified cytosines are hydroxymethylated in adult human brain, a significant proportion of which are highly-hydroxymethylated with enrichment in active genic regions and distal-regulatory elements. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL11154
4 Samples
Download data: TXT
Series
Accession:
GSE46710
ID:
200046710
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

Fe_Front.TAB-Seq (single)

Organism:
Homo sapiens
Source name:
Fetal brain prefrontal cortex tissue
Platform:
GPL11154
Series:
GSE46710
Download data
Sample
Accession:
GSM1135084
ID:
301135084
4.

Fe_Front.TAB-Seq (paired-end)

Organism:
Homo sapiens
Source name:
Fetal brain prefrontal cortex tissue
Platform:
GPL11154
Series:
GSE46710
Download data
Sample
Accession:
GSM1135083
ID:
301135083
5.

Ad_Front.TAB-Seq

Organism:
Homo sapiens
Source name:
Adult brain prefrontal cortex tissue
Platform:
GPL11154
Series:
GSE46710
Download data
Sample
Accession:
GSM1135082
ID:
301135082
6.

Ad_Front.MethylC-Seq

Organism:
Homo sapiens
Source name:
Adult brain prefrontal cortex tissue
Platform:
GPL11154
Series:
GSE46710
Download data
Sample
Accession:
GSM1135081
ID:
301135081
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Supplemental Content

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