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Items: 6

1.

Genome-wide maps of H3K4me3 and H3K27me3 in human FOXP3+ Treg cells and the corresponding FOXP3-losing cells

(Submitter supplied) Natural CD4+FOXP3+ regulatory T (Treg) cells constitute a unique T-cell lineage that plays a pivotal role in maintaining immune homeostasis and immune tolerance. Recent studies provide evidence for the heterogeneity and plasticity of the Treg cell lineage. However, the fate of human Treg cells after loss of FOXP3 expression and the underlying epigenetic mechanisms remain to be fully elucidated. Here, we compared gene expression profiles and histone methylation status on two histone H3 lysine residues (H3K4me3 and H3K27me3) of expanded FOXP3+ and corresponding FOXP3-losing Treg cells. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
4 Samples
Download data: WIG
Series
Accession:
GSE47510
ID:
200047510
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

expanded FOXP3-losing H3K27me3

Organism:
Homo sapiens
Source name:
CD4+CD25highCD127low/- Treg cells
Platform:
GPL11154
Series:
GSE47510 GSE47747
Download data: WIG
Sample
Accession:
GSM1151312
ID:
301151312
4.

expanded FOXP3-losing H3K4me3

Organism:
Homo sapiens
Source name:
CD4+CD25highCD127low/- Treg cells
Platform:
GPL11154
Series:
GSE47510 GSE47747
Download data: WIG
Sample
Accession:
GSM1151311
ID:
301151311
5.

expanded FOXP3+ H3K27me3

Organism:
Homo sapiens
Source name:
CD4+CD25highCD127low/- Treg cells
Platform:
GPL11154
Series:
GSE47510 GSE47747
Download data: WIG
Sample
Accession:
GSM1151310
ID:
301151310
6.

expanded FOXP3+ H3K4me3

Organism:
Homo sapiens
Source name:
CD4+CD25highCD127low/- Treg cells
Platform:
GPL11154
Series:
GSE47510 GSE47747
Download data: WIG
Sample
Accession:
GSM1151309
ID:
301151309
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Supplemental Content

db=gds|term=GSE47510[Accession]|query=1|qty=2|blobid=MCID_6642b8475f31ac491174bc8e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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