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Items: 5

1.

Genome-wide ChIP-Seq analysis of genomic Stat3 binding sites in murine gastric tumors following stimulation with IL6 or IL11 (MACS)

(Submitter supplied) The latent transcription factor STAT3 is a point of convergence for numerous oncogenic signaling pathways and is excessively activated in the majority of human epithelial cancers. STAT3 promotes many hallmarks of cancer including enhanced proliferation, increased survival, sustained angiogenesis, immune evasion and tumor-promoting inflammation. We performed chromatin immunoprecipitations (ChIP) followed by next-generation sequencing (ChIP-Seq) to identify genomic Stat3 binding sites in established gastric tumors of gp130F/F mutant mice (Tebbutt et al., 2002) following administration of recombinant human interleukin (IL)-6 or IL11. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL9250
3 Samples
Download data: BED, XLS
Series
Accession:
GSE48285
ID:
200048285
2.

Illumina Genome Analyzer II (Mus musculus)

Platform
Accession:
GPL9250
ID:
100009250
3.

Tumors IL11 (MACS)

Organism:
Mus musculus
Source name:
Pooled gastric tumor tissue from 3 individual IL11-treated gp130F/F mice, Stat3 ChIP
Platform:
GPL9250
Series:
GSE48285 GSE48288
Download data: BED, XLS
Sample
Accession:
GSM1174213
ID:
301174213
4.

Tumors IL6 (MACS)

Organism:
Mus musculus
Source name:
Pooled gastric tumor tissue from 3 individual IL6-treated gp130F/F mice, Stat3 ChIP
Platform:
GPL9250
Series:
GSE48285 GSE48288
Download data: BED, XLS
Sample
Accession:
GSM1174212
ID:
301174212
5.

Tumors PBS Control (MACS)

Organism:
Mus musculus
Source name:
Pooled gastric tumor tissue from 3 individual PBS-treated gp130F/F mice, Stat3 ChIP
Platform:
GPL9250
Series:
GSE48285 GSE48288
Download data: BED, XLS
Sample
Accession:
GSM1174211
ID:
301174211
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Supplemental Content

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