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Items: 13

1.

SUMOylation Regulates the Anti-Proliferative Gene Signature Programs of Glucocorticoid Receptor (ChIP-seq)

(Submitter supplied) In addition to the glucocorticoids, the glucocorticoid receptor (GR) is regulated by post-translational modifications, including SUMOylation. We have analyzed how SUMOylation influences the activity of endogenous GR target genes and the receptor chromatin binding by using isogenic HEK293 cells expressing wild-type GR (wtGR) or SUMOylation-defective GR (GR3KR). Gene expression profiling revealed that both dexamethasone up- and down-regulated genes are affected by the GR sumoylation and that the affected genes are significantly associated with pathways of cellular proliferation and survival. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
11 Samples
Download data: BED
Series
Accession:
GSE48374
ID:
200048374

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10400 Series
180082 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

FRT_dex_IgG

Organism:
Homo sapiens
Source name:
Isogenic HEK293 Cells
Platform:
GPL11154
Series:
GSE48374 GSE48379
Download data
Sample
Accession:
GSM1176708
ID:
301176708

SRA Run Selector

4.

3KR_dex_SUMO_2_3_rep2

Organism:
Homo sapiens
Source name:
Isogenic HEK293 Cells
Platform:
GPL11154
Series:
GSE48374 GSE48379
Download data: BED
Sample
Accession:
GSM1176707
ID:
301176707

SRA Run Selector

5.

3KR_dex_SUMO_2_3_rep1

Organism:
Homo sapiens
Source name:
Isogenic HEK293 Cells
Platform:
GPL11154
Series:
GSE48374 GSE48379
Download data: BED
Sample
Accession:
GSM1176706
ID:
301176706

SRA Run Selector

6.

wt_dex_SUMO_2_3_rep2

Organism:
Homo sapiens
Source name:
Isogenic HEK293 Cells
Platform:
GPL11154
Series:
GSE48374 GSE48379
Download data: BED
Sample
Accession:
GSM1176705
ID:
301176705

SRA Run Selector

7.

wt_dex_SUMO_2_3_rep1

Organism:
Homo sapiens
Source name:
Isogenic HEK293 Cells
Platform:
GPL11154
Series:
GSE48374 GSE48379
Download data: BED
Sample
Accession:
GSM1176704
ID:
301176704

SRA Run Selector

8.

FRT_input

Organism:
Homo sapiens
Source name:
Isogenic HEK293 Cells
Platform:
GPL11154
Series:
GSE48374 GSE48379
Download data
Sample
Accession:
GSM1176703
ID:
301176703

SRA Run Selector

9.

FRT_dex_GR

Organism:
Homo sapiens
Source name:
Isogenic HEK293 Cells
Platform:
GPL11154
Series:
GSE48374 GSE48379
Download data: BED
Sample
Accession:
GSM1176702
ID:
301176702

SRA Run Selector

10.

3KR_dex_GR_rep2

Organism:
Homo sapiens
Source name:
Isogenic HEK293 Cells
Platform:
GPL11154
Series:
GSE48374 GSE48379
Download data: BED
Sample
Accession:
GSM1176701
ID:
301176701

SRA Run Selector

11.

3KR_dex_GR_rep1

Organism:
Homo sapiens
Source name:
Isogenic HEK293 Cells
Platform:
GPL11154
Series:
GSE48374 GSE48379
Download data: BED
Sample
Accession:
GSM1176700
ID:
301176700

SRA Run Selector

12.

wt_dex_GR_rep2

Organism:
Homo sapiens
Source name:
Isogenic HEK293 Cells
Platform:
GPL11154
Series:
GSE48374 GSE48379
Download data: BED
Sample
Accession:
GSM1176699
ID:
301176699

SRA Run Selector

13.

wt_dex_GR_rep1

Organism:
Homo sapiens
Source name:
Isogenic HEK293 Cells
Platform:
GPL11154
Series:
GSE48374 GSE48379
Download data: BED
Sample
Accession:
GSM1176698
ID:
301176698

SRA Run Selector

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