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Items: 11

1.

Genome-wide methylation maps for Proliferating and Senescent cells

(Submitter supplied) Altered DNA methylation and associated destabilization of genome integrity and function is a hallmark of cancer. Replicative senescence imposes a limit on proliferative potential that all cancer cells must bypass. Compared to proliferating cells, senescent cells exhibit marked chromatin re-organization. Here we show by whole-genome single-nucleotide bisulfite sequencing that replicative senescent human cells exhibit widespread alterations in their DNA methylome. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL11154
9 Samples
Download data: BED, BIGWIG, TXT
Series
Accession:
GSE48580
ID:
200048580
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

SV40 tAg BS-seq Rep3

Organism:
Homo sapiens
Source name:
cells bypassing senescence
Platform:
GPL11154
Series:
GSE48580
Download data: BIGWIG, TXT
Sample
Accession:
GSM1181659
ID:
301181659
4.

SV40 tAg BS-seq Rep2

Organism:
Homo sapiens
Source name:
cells bypassing senescence
Platform:
GPL11154
Series:
GSE48580
Download data: BIGWIG, TXT
Sample
Accession:
GSM1181657
ID:
301181657
5.

SV40 tAg BS-seq Rep1

Organism:
Homo sapiens
Source name:
cells bypassing senescence
Platform:
GPL11154
Series:
GSE48580
Download data: BIGWIG, TXT
Sample
Accession:
GSM1181655
ID:
301181655
6.

Senescent BS-seq Rep3

Organism:
Homo sapiens
Source name:
senescent cells
Platform:
GPL11154
Series:
GSE48580
Download data: BIGWIG, TXT
Sample
Accession:
GSM1181652
ID:
301181652
7.

Senescent BS-seq Rep2

Organism:
Homo sapiens
Source name:
senescent cells
Platform:
GPL11154
Series:
GSE48580
Download data: BIGWIG, TXT
Sample
Accession:
GSM1181650
ID:
301181650
8.

Senescent BS-seq Rep1

Organism:
Homo sapiens
Source name:
senescent cells
Platform:
GPL11154
Series:
GSE48580
Download data: BIGWIG, TXT
Sample
Accession:
GSM1181649
ID:
301181649
9.

Proliferating BS-seq Rep3

Organism:
Homo sapiens
Source name:
proliferating cells
Platform:
GPL11154
Series:
GSE48580
Download data: BIGWIG, TXT
Sample
Accession:
GSM1181647
ID:
301181647
10.

Proliferating BS-seq Rep2

Organism:
Homo sapiens
Source name:
proliferating cells
Platform:
GPL11154
Series:
GSE48580
Download data: BIGWIG, TXT
Sample
Accession:
GSM1181646
ID:
301181646
11.

Proliferating BS-seq Rep1

Organism:
Homo sapiens
Source name:
proliferating cells
Platform:
GPL11154
Series:
GSE48580
Download data: BIGWIG, TXT
Sample
Accession:
GSM1181642
ID:
301181642
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Supplemental Content

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