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Items: 8

1.

Activation of the P-TEFb Complex by Lethal Prostate Cancer-Associated Enhancer RNAs [ChIP-Seq]

(Submitter supplied) Castration resistant prostate cancer (CRPC) is a lethal disease1-4. Aberrant activation of the androgen receptor (AR) becomes a central mechanism contributing to the resistance of endocrine therapies2,3. Here we demonstrate that non-coding RNAs transcribed from the AR bound-enhancers RNAs (AR-eRNAs) are upregulated in human CRPC cells in vitro, xenografts in vivo and patient tissues. Expression of a subset of genes with elevated AR-eRNAs, including TLE1 and HTR3A, is inversely correlated with biochemical recurrence-free survival of CRPC patients. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
6 Samples
Download data: BEDGRAPH
Series
Accession:
GSE55031
ID:
200055031
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

LNCaP_input

Organism:
Homo sapiens
Source name:
prostate cancer cell
Platform:
GPL11154
Series:
GSE55031 GSE55032
Download data: BEDGRAPH
Sample
Accession:
GSM1328170
ID:
301328170
4.

LNCaP_Mib

Organism:
Homo sapiens
Source name:
prostate cancer cell
Platform:
GPL11154
Series:
GSE55031 GSE55032
Download data: BEDGRAPH
Sample
Accession:
GSM1328169
ID:
301328169
5.

LNCaP_EtOH

Organism:
Homo sapiens
Source name:
prostate cancer cell
Platform:
GPL11154
Series:
GSE55031 GSE55032
Download data: BEDGRAPH
Sample
Accession:
GSM1328168
ID:
301328168
6.

C4-2_input

Organism:
Homo sapiens
Source name:
prostate cancer cell
Platform:
GPL11154
Series:
GSE55031 GSE55032
Download data: BEDGRAPH
Sample
Accession:
GSM1328167
ID:
301328167
7.

C4-2_Mib

Organism:
Homo sapiens
Source name:
prostate cancer cell
Platform:
GPL11154
Series:
GSE55031 GSE55032
Download data: BEDGRAPH
Sample
Accession:
GSM1328166
ID:
301328166
8.

C4-2_EtOH

Organism:
Homo sapiens
Source name:
prostate cancer cell
Platform:
GPL11154
Series:
GSE55031 GSE55032
Download data: BEDGRAPH
Sample
Accession:
GSM1328165
ID:
301328165
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Supplemental Content

db=gds|term=GSE55031[Accession]|query=1|qty=2|blobid=MCID_666f92b9ce9c6e4cac146b8c|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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