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Items: 17

1.

Modeling Familial Cancer with iPSC Approaches

(Submitter supplied) In vitro modeling of human disease has recently become feasible with the adoption of induced pluripotent stem cell (iPSC) technology. Here, we established patient-derived iPSCs from an Li-Fraumeni Syndrome (LFS) family and investigated the role of mutant p53 in the development of osteosarcoma (OS). Several members of this family carried a heterozygous p53(G245D) mutation and presented with a broad spectrum of tumors including OS. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL16791 GPL11154
14 Samples
Download data: TXT
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

LFS2-D_tumor

Organism:
Homo sapiens
Source name:
induced pluripotent stem cell derived mesenchymal stem cell
Platform:
GPL16791
Series:
GSE58123
Download data
Sample
Accession:
GSM1652553
ID:
301652553
5.

LFS2-B_tumor

Organism:
Homo sapiens
Source name:
induced pluripotent stem cell derived mesenchymal stem cell
Platform:
GPL16791
Series:
GSE58123
Download data
Sample
Accession:
GSM1652552
ID:
301652552
6.

WT1-A_day17

Organism:
Homo sapiens
Source name:
WT-derived osteoblast
Platform:
GPL11154
Series:
GSE58123
Download data
Sample
Accession:
GSM1401380
ID:
301401380
7.

WT1-A_day14

Organism:
Homo sapiens
Source name:
WT-derived MSCs intermediate
Platform:
GPL11154
Series:
GSE58123
Download data
Sample
Accession:
GSM1401379
ID:
301401379
8.

WT1-A_day7

Organism:
Homo sapiens
Source name:
WT-derived MSCs intermediate
Platform:
GPL11154
Series:
GSE58123
Download data
Sample
Accession:
GSM1401378
ID:
301401378
9.

WT1-A_day0

Organism:
Homo sapiens
Source name:
WT-derived MSCs
Platform:
GPL11154
Series:
GSE58123
Download data
Sample
Accession:
GSM1401377
ID:
301401377
10.

LFS2-B_day17

Organism:
Homo sapiens
Source name:
LFS-derived osteoblast
Platform:
GPL11154
Series:
GSE58123
Download data
Sample
Accession:
GSM1401376
ID:
301401376
11.

LFS2-B_day14

Organism:
Homo sapiens
Source name:
LFS-derived MSCs intermediate
Platform:
GPL11154
Series:
GSE58123
Download data
Sample
Accession:
GSM1401375
ID:
301401375
12.

LFS2-B_day7

Organism:
Homo sapiens
Source name:
LFS-derived MSCs intermediate
Platform:
GPL11154
Series:
GSE58123
Download data
Sample
Accession:
GSM1401374
ID:
301401374
13.

LFS2-B_day0

Organism:
Homo sapiens
Source name:
LFS-derived MSCs
Platform:
GPL11154
Series:
GSE58123
Download data
Sample
Accession:
GSM1401373
ID:
301401373
14.

LFS1-A_day17

Organism:
Homo sapiens
Source name:
LFS-derived osteoblast
Platform:
GPL11154
Series:
GSE58123
Download data
Sample
Accession:
GSM1401372
ID:
301401372
15.

LFS1-A_day14

Organism:
Homo sapiens
Source name:
LFS-derived MSCs intermediate
Platform:
GPL11154
Series:
GSE58123
Download data
Sample
Accession:
GSM1401371
ID:
301401371
16.

LFS1-A_day7

Organism:
Homo sapiens
Source name:
LFS-derived MSCs intermediate
Platform:
GPL11154
Series:
GSE58123
Download data
Sample
Accession:
GSM1401370
ID:
301401370
17.

LFS1-A_day0

Organism:
Homo sapiens
Source name:
LFS-derived MSCs
Platform:
GPL11154
Series:
GSE58123
Download data
Sample
Accession:
GSM1401369
ID:
301401369
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Supplemental Content

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