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Items: 1 to 20 of 23

1.

SMO variants explain the majority of drug resistance in basal cell carcinoma [RNA-Seq]

(Submitter supplied) Advanced basal cell carcinomas (BCCs) frequently acquire resistance to Smoothened (SMO) inhibitors through unknown mechanisms, providing a unique opportunity to study human tumor evolution. Here, we identify SMO mutations in 50% (22/44) of resistant BCCs compared with 5.6% (2/36) of untreated BCCs (p<0.0001), and show that these mutations maintain Hedgehog signaling in the presence of SMO inhibitors. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
21 Samples
Download data: XLSX
Series
Accession:
GSE58375
ID:
200058375

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
11830 Series
336732 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

3.

RNASeq_Sensitive4

Organism:
Homo sapiens
Source name:
sensitive basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409354
ID:
301409354

SRA Run Selector

4.

RNASeq_Sensitive3

Organism:
Homo sapiens
Source name:
sensitive basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409353
ID:
301409353

SRA Run Selector

5.

RNASeq_Sensitive2

Organism:
Homo sapiens
Source name:
sensitive basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409352
ID:
301409352

SRA Run Selector

6.

RNASeq_Sensitive1

Organism:
Homo sapiens
Source name:
sensitive basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409351
ID:
301409351

SRA Run Selector

7.

RNASeq_Resistance9

Organism:
Homo sapiens
Source name:
resistant basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409350
ID:
301409350

SRA Run Selector

8.

RNASeq_Resistance8

Organism:
Homo sapiens
Source name:
resistant basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409349
ID:
301409349

SRA Run Selector

9.

RNASeq_Resistance7

Organism:
Homo sapiens
Source name:
resistant basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409348
ID:
301409348

SRA Run Selector

10.

RNASeq_Resistance6

Organism:
Homo sapiens
Source name:
resistant basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409347
ID:
301409347

SRA Run Selector

11.

RNASeq_Resistance5

Organism:
Homo sapiens
Source name:
resistant basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409346
ID:
301409346

SRA Run Selector

12.

RNASeq_Resistance4

Organism:
Homo sapiens
Source name:
resistant basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409345
ID:
301409345

SRA Run Selector

13.

RNASeq_Resistance3

Organism:
Homo sapiens
Source name:
resistant basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409344
ID:
301409344

SRA Run Selector

14.

RNASeq_Resistance2

Organism:
Homo sapiens
Source name:
resistant basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409343
ID:
301409343

SRA Run Selector

15.

RNASeq_Resistance1

Organism:
Homo sapiens
Source name:
resistant basal cell cancers
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409342
ID:
301409342

SRA Run Selector

16.

RNASeq_Normal8

Organism:
Homo sapiens
Source name:
normal skin biopsies
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409341
ID:
301409341

SRA Run Selector

17.

RNASeq_Normal7

Organism:
Homo sapiens
Source name:
normal skin biopsies
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409340
ID:
301409340

SRA Run Selector

18.

RNASeq_Normal6

Organism:
Homo sapiens
Source name:
normal skin biopsies
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409339
ID:
301409339

SRA Run Selector

19.

RNASeq_Normal5

Organism:
Homo sapiens
Source name:
normal skin biopsies
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409338
ID:
301409338

SRA Run Selector

20.

RNASeq_Normal4

Organism:
Homo sapiens
Source name:
normal skin biopsies
Platform:
GPL16791
Series:
GSE58375 GSE58377
Download data
Sample
Accession:
GSM1409337
ID:
301409337

SRA Run Selector

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db=gds|term=GSE58375[Accession]|query=1|qty=2|blobid=MCID_6654c7a7e795547e5fa737a1|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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