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Items: 5

1.

Physical and functional CSL-p53 interactions underlie control of cancer stromal cell evolution [ChIP-seq]

(Submitter supplied) Senescence of stromal fibroblasts has been linked to establishment of cancer associated fibroblasts (CAF) and aging-associated increase of tumors. However, in clinically occurring carcinomas, density and proliferation of CAFs are frequently increased rather than decreased. We previously showed that genetic deletion or down-modulation of the canonical Notch effector CSL/RBP-Jκ in skin dermal fibroblasts is sufficient for CAF activation with consequent development of multifocal keratinocyte tumors. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
3 Samples
Download data: BED
Series
Accession:
GSE59942
ID:
200059942
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

Input DNA

Organism:
Homo sapiens
Source name:
primary dermal fibroblasts
Platform:
GPL11154
Series:
GSE59942 GSE65474
Download data
Sample
Accession:
GSM1462554
ID:
301462554
4.

CSL ChIPSeq_HomeMade Ab

Organism:
Homo sapiens
Source name:
primary dermal fibroblasts
Platform:
GPL11154
Series:
GSE59942 GSE65474
Download data: BED
Sample
Accession:
GSM1462553
ID:
301462553
5.

CSL ChIPSeq_CellSignalling Ab

Organism:
Homo sapiens
Source name:
primary dermal fibroblasts
Platform:
GPL11154
Series:
GSE59942 GSE65474
Download data: BED
Sample
Accession:
GSM1462552
ID:
301462552
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Supplemental Content

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