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Items: 6

1.

Inhibitors of LSD1 target demethylase-independent activity to induce differentiation in acute myeloid leukemia [RNA-Seq experiments]

(Submitter supplied) To determine whether changes in histone modifications directly correlate with changes in transcription, THP1 AML cells were treated with a potent and selective LSD1 inhibitor (OG86) and then subjected to concomitant RNA sequencing (RNAseq) and ChIP sequencing (ChIPseq) for monomethyl-, dimethyl- and trimethyl histone H3 modifications.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16558
4 Samples
Download data: TXT
2.

AB 5500 Genetic Analyzer (Homo sapiens)

Platform
Accession:
GPL16558
ID:
100016558
3.

THP1_OG86_replicate2

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16558
Series:
GSE63217 GSE63222
Download data
Sample
Accession:
GSM1543975
ID:
301543975
4.

THP1_OG86_replicate1

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16558
Series:
GSE63217 GSE63222
Download data
Sample
Accession:
GSM1543974
ID:
301543974
5.

THP1_DMSO_replicate2

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16558
Series:
GSE63217 GSE63222
Download data
Sample
Accession:
GSM1543973
ID:
301543973
6.

THP1_DMSO_replicate1

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16558
Series:
GSE63217 GSE63222
Download data
Sample
Accession:
GSM1543972
ID:
301543972
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Supplemental Content

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