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Items: 8

1.

Inhibitors of LSD1 target demethylase-independent activity to induce differentiation in acute myeloid leukemia [ChIP-Seq: histone modifications]

(Submitter supplied) To determine whether changes in histone modifications directly correlate with changes in transcription, THP1 AML cells were treated with a potent and selective LSD1 inhibitor (OG86) and then subjected to concomitant RNA sequencing (RNAseq) and ChIP sequencing (ChIPseq) for monomethyl-, dimethyl- and trimethyl histone H3 modifications.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL16791
6 Samples
Download data: TXT
Series
Accession:
GSE63218
ID:
200063218
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

H3K4Me3_OG86

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16791
Series:
GSE63218 GSE63222
Download data: TXT
Sample
Accession:
GSM1543981
ID:
301543981
4.

H3K4Me3_DMSO

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16791
Series:
GSE63218 GSE63222
Download data: TXT
Sample
Accession:
GSM1543980
ID:
301543980
5.

H3K4Me2_OG86

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16791
Series:
GSE63218 GSE63222
Download data: TXT
Sample
Accession:
GSM1543979
ID:
301543979
6.

H3K4Me2_DMSO

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16791
Series:
GSE63218 GSE63222
Download data: TXT
Sample
Accession:
GSM1543978
ID:
301543978
7.

H3K4Me1_OG86

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16791
Series:
GSE63218 GSE63222
Download data: TXT
Sample
Accession:
GSM1543977
ID:
301543977
8.

H3K4Me1_DMSO

Organism:
Homo sapiens
Source name:
THP1 cells
Platform:
GPL16791
Series:
GSE63218 GSE63222
Download data: TXT
Sample
Accession:
GSM1543976
ID:
301543976
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Supplemental Content

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