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Items: 12

1.

ALKBH1-Mediated Transfer RNA Demethylation

(Submitter supplied) Transfer RNA (tRNA) is a central component of protein synthesis and cell signaling network. One salient feature of tRNA is its heavily modified status, which can critically impact its function. Here we show that mammalian ALKBH1 is a tRNA demethylase. It mediates the demethylation of N1-methyladenosine (m1A) in tRNAs. The ALKBH1-catalyzed demethylation of the target tRNAs results in their reduced partition in polysomes and their decreased usage in protein synthesis. more...
Organism:
Mus musculus; Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL16791 GPL17021
9 Samples
Download data: TXT
Series
Accession:
GSE65299
ID:
200065299

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Mus musculus)

Organism:
Mus musculus
10744 Series
292828 Samples
Download data
Platform
Accession:
GPL17021
ID:
100017021

3.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
11813 Series
336528 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

4.

CLIP-control replicate 2

Organism:
Homo sapiens
Source name:
CLIP-control replicate 2
Platform:
GPL16791
Series:
GSE65299
Download data: TXT
Sample
Accession:
GSM2107202
ID:
302107202

SRA Run Selector

5.

CLIP-control replicate 1

Organism:
Homo sapiens
Source name:
CLIP-control replicate 1
Platform:
GPL16791
Series:
GSE65299
Download data: TXT
Sample
Accession:
GSM2107201
ID:
302107201

SRA Run Selector

6.

CLIP-ALKBH1-replicate3

Organism:
Homo sapiens
Source name:
CLIP-ALKBH1-replicate3
Platform:
GPL16791
Series:
GSE65299
Download data: TXT
Sample
Accession:
GSM2107200
ID:
302107200

SRA Run Selector

7.

tRNA-seq Alkbh1 KO MEF Replicate 2

Organism:
Mus musculus
Source name:
tRNA-seq Alkbh1 KO MEF
Platform:
GPL17021
Series:
GSE65299
Download data: TXT
Sample
Accession:
GSM2323456
ID:
302323456

SRA Run Selector

8.

CLIP-ALKBH1-replicate2

Organism:
Homo sapiens
Source name:
CLIP-ALKBH1-replicate2
Platform:
GPL16791
Series:
GSE65299
Download data: TXT
Sample
Accession:
GSM2107199
ID:
302107199

SRA Run Selector

9.

tRNA-seq Alkbh1 KO MEF Replicate 1

Organism:
Mus musculus
Source name:
tRNA-seq Alkbh1 KO MEF
Platform:
GPL17021
Series:
GSE65299
Download data: TXT
Sample
Accession:
GSM2323455
ID:
302323455

SRA Run Selector

10.

CLIP-ALKBH1-replicate1

Organism:
Homo sapiens
Source name:
CLIP-ALKBH1-replicate1
Platform:
GPL16791
Series:
GSE65299
Download data: TXT
Sample
Accession:
GSM2107198
ID:
302107198

SRA Run Selector

11.

tRNA-seq wild-type MEF Replicate 2

Organism:
Mus musculus
Source name:
tRNA-seq wild-type MEF
Platform:
GPL17021
Series:
GSE65299
Download data: TXT
Sample
Accession:
GSM2323454
ID:
302323454

SRA Run Selector

12.

tRNA-seq wild-type MEF Replicate 1

Organism:
Mus musculus
Source name:
tRNA-seq wild-type MEF
Platform:
GPL17021
Series:
GSE65299
Download data: TXT
Sample
Accession:
GSM2323453
ID:
302323453

SRA Run Selector

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