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Items: 14

1.

Histone H3 globular domain acetylation identifies new class of enhancers

(Submitter supplied) We report the acetylation of lysine residues in the globular domain of H3 (H3K64ac and H3K122ac) marks active gene promoters and also a subset of active enhancers in mouse embryonic stem cells (mESCs), human erythroleukemic cell line (K562). Moreover, we find a novel class of active functional enhancers in ESCs that are marked by H3K122ac but which lack H3K27ac. This work suggests that a more complex analysis of histone acetylation is required to identify enhancers than was previously considered.
Organism:
Homo sapiens; Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL13112 GPL16791 GPL17021
10 Samples
Download data: BED, BEDGRAPH
Series
Accession:
GSE66023
ID:
200066023
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
4.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
5.

46c_H3K64ac_rep1

Organism:
Mus musculus
Source name:
46c_H3K64ac
Platform:
GPL13112
Series:
GSE66023
Download data
Sample
Accession:
GSM2054691
ID:
302054691
6.

46c_H3K122ac_rep1

Organism:
Mus musculus
Source name:
46c_H3K122ac
Platform:
GPL13112
Series:
GSE66023
Download data
Sample
Accession:
GSM2054689
ID:
302054689
7.

46c_H3K27ac_rep2

Organism:
Mus musculus
Source name:
46c_H3K27ac
Platform:
GPL17021
Series:
GSE66023
Download data
Sample
Accession:
GSM2054694
ID:
302054694
8.

46c_H3K27ac_rep1

Organism:
Mus musculus
Source name:
46c_H3K27ac
Platform:
GPL17021
Series:
GSE66023
Download data
Sample
Accession:
GSM2054693
ID:
302054693
9.

46c_H3K64ac_rep2

Organism:
Mus musculus
Source name:
46c_H3K64ac
Platform:
GPL17021
Series:
GSE66023
Download data
Sample
Accession:
GSM2054692
ID:
302054692
10.

46c_H3K122ac_rep2

Organism:
Mus musculus
Source name:
46c_H3K122ac
Platform:
GPL17021
Series:
GSE66023
Download data
Sample
Accession:
GSM2054690
ID:
302054690
11.

K562_Input

Organism:
Homo sapiens
Source name:
K562_Input
Platform:
GPL16791
Series:
GSE66023
Download data
Sample
Accession:
GSM2054698
ID:
302054698
12.

K562_H3K4me1

Organism:
Homo sapiens
Source name:
K562_H3K4me1
Platform:
GPL16791
Series:
GSE66023
Download data: BED, BEDGRAPH
Sample
Accession:
GSM2054697
ID:
302054697
13.

K562_H3K27ac

Organism:
Homo sapiens
Source name:
K562_H3K27ac
Platform:
GPL16791
Series:
GSE66023
Download data: BED, BEDGRAPH
Sample
Accession:
GSM2054696
ID:
302054696
14.

K562_H3K122ac

Organism:
Homo sapiens
Source name:
K562_H3K122ac
Platform:
GPL16791
Series:
GSE66023
Download data: BED, BEDGRAPH
Sample
Accession:
GSM2054695
ID:
302054695
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Supplemental Content

db=gds|term=GSE66023[Accession]|query=1|qty=3|blobid=MCID_6651f30bd01e38019cd5fd9d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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