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Items: 5

1.

RNA-seq analysis of add-back rescued TALEN-mediated LATS2 knockout HeLa-S3 cells

(Submitter supplied) Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular contexts remain poorly understood. Here, we discovered that LATS2 knockout causes dysregulation of PRC2 and subsequent transcriptome changes for differentiation in both mouse and human cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
3 Samples
Download data: TXT
Series
Accession:
GSE66388
ID:
200066388

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
11814 Series
336528 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

3.

HeLa-S3_LATS2_KO+KD

Organism:
Homo sapiens
Source name:
HeLa-S3 cell, LATS2 KO, rescued by kinase-dead LATS2, clone#21
Platform:
GPL16791
Series:
GSE63538 GSE66388
Download data: TXT
Sample
Accession:
GSM1621379
ID:
301621379

SRA Run Selector

4.

HeLa-S3_LATS2_KO+WT

Organism:
Homo sapiens
Source name:
HeLa-S3 cell, LATS2 KO, rescued by wild-type LATS2, clone#21
Platform:
GPL16791
Series:
GSE63538 GSE66388
Download data: TXT
Sample
Accession:
GSM1621378
ID:
301621378

SRA Run Selector

5.

HeLa-S3_LATS2_KO+EV

Organism:
Homo sapiens
Source name:
HeLa-S3 cell, LATS2 KO, rescued by empty vector, clone#3
Platform:
GPL16791
Series:
GSE63538 GSE66388
Download data: TXT
Sample
Accession:
GSM1621377
ID:
301621377

SRA Run Selector

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