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Items: 6

1.

RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships RDIP-seq)

(Submitter supplied) Mapping of RNA:DNA hybrids in human cells reveals a number of characteristics of these non-canonical nucleic acid structures. A directional sequencing approach reveals the RNA component of the RNA:DNA hybrid to be purine-rich, indicating a thermodynamic contribution to the stability of these structures. The RNA:DNA hybrids are enriched at loci with decreased DNA methylation and increased DNase hypersensitivity, and within larger domains with characteristics of heterochromatin formation. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL16791
4 Samples
Download data: TXT
Series
Accession:
GSE68948
ID:
200068948
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

HEK293T_Input

Organism:
Homo sapiens
Source name:
HEK293T cells
Platform:
GPL16791
Series:
GSE68948 GSE68953
Download data
Sample
Accession:
GSM1687557
ID:
301687557
4.

HEK293T_RDIP

Organism:
Homo sapiens
Source name:
HEK293T cells
Platform:
GPL16791
Series:
GSE68948 GSE68953
Download data
Sample
Accession:
GSM1687556
ID:
301687556
5.

IMR90_Input

Organism:
Homo sapiens
Source name:
IMR-90 cells (ATCC CCL-186)
Platform:
GPL16791
Series:
GSE68948 GSE68953
Download data
Sample
Accession:
GSM1687555
ID:
301687555
6.

IMR90_RDIP

Organism:
Homo sapiens
Source name:
IMR-90 cells (ATCC CCL-186)
Platform:
GPL16791
Series:
GSE68948 GSE68953
Download data
Sample
Accession:
GSM1687554
ID:
301687554
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Supplemental Content

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