GSE69656[Accession] - GEO DataSets - NCBI

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Items: 17

Select item 2000696561.

An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates

(Submitter supplied) Alternative splicing (AS) generates extensive transcriptomic and proteomic complexity. However, the functions of species- and lineage-specific splice variants are largely unknown. Here, we show that mammalian-specific skipping of exon 9 of PTBP1 alters its splicing regulatory activities and affects the inclusion levels of numerous exons. During neurogenesis, skipping of exon 9 reduces PTBP1 repressive activity so as to facilitate activation of a brain-specific AS program. more...

Organism:: Homo sapiens; Gallus gallus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL16791 GPL19005
14 Samples

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Series

Accession:: GSE69656

ID:: 200069656

PubMed Similar studies SRA Run Selector

Select item 1000190052.

Illumina HiSeq 2500 (Gallus gallus)

Organism:: Gallus gallus

144 Series
4588 Samples

Platform

Accession:: GPL19005

ID:: 100019005

Select item 1000167913.

Illumina HiSeq 2500 (Homo sapiens)

Organism:: Homo sapiens

11814 Series
336528 Samples

Platform

Accession:: GPL16791

ID:: 100016791

Select item 3017053884.

dt40 homozygous exon 8 deletion_rep2

Organism:: Gallus gallus

Source name:: DT40-Cre1 pre-B-cell line

Platform:: GPL19005
Series:: GSE69656

Sample

Accession:: GSM1705388

ID:: 301705388

SRA Run Selector

Select item 3017053875.

dt40 homozygous exon 8 deletion_rep1

Organism:: Gallus gallus

Source name:: DT40-Cre1 pre-B-cell line

Platform:: GPL19005
Series:: GSE69656

Sample

Accession:: GSM1705387

ID:: 301705387

SRA Run Selector

Select item 3017053866.

dt40 heterozygous exon 8 deletion_rep2

Organism:: Gallus gallus

Source name:: DT40-Cre1 pre-B-cell line

Platform:: GPL19005
Series:: GSE69656

Sample

Accession:: GSM1705386

ID:: 301705386

SRA Run Selector

Select item 3017053857.

dt40 heterozygous exon 8 deletion_rep1

Organism:: Gallus gallus

Source name:: DT40-Cre1 pre-B-cell line

Platform:: GPL19005
Series:: GSE69656

Sample

Accession:: GSM1705385

ID:: 301705385

SRA Run Selector

Select item 3017053848.

dt40 wildtype_rep2

Organism:: Gallus gallus

Source name:: DT40-Cre1 pre-B-cell line

Platform:: GPL19005
Series:: GSE69656

Sample

Accession:: GSM1705384

ID:: 301705384

SRA Run Selector

Select item 3017053839.

dt40 wildtype_rep1

Organism:: Gallus gallus

Source name:: DT40-Cre1 pre-B-cell line

Platform:: GPL19005
Series:: GSE69656

Sample

Accession:: GSM1705383

ID:: 301705383

SRA Run Selector

Select item 30170538210.

293 PTBP1 and PTBP2 double knockdown with exon-excluded PTBP1 overexpression_rep2

Organism:: Homo sapiens

Source name:: Flp-In™ T-REx™ 293 Cell Line

Platform:: GPL16791
Series:: GSE69656

Sample

Accession:: GSM1705382

ID:: 301705382

SRA Run Selector

Select item 30170538111.

293 PTBP1 and PTBP2 double knockdown with exon-excluded PTBP1 overexpression_rep1

Organism:: Homo sapiens

Source name:: Flp-In™ T-REx™ 293 Cell Line

Platform:: GPL16791
Series:: GSE69656

Sample

Accession:: GSM1705381

ID:: 301705381

SRA Run Selector

Select item 30170538012.

293 PTBP1 and PTBP2 double knockdown with full-length PTBP1 overexpression_rep2

Organism:: Homo sapiens

Source name:: Flp-In™ T-REx™ 293 Cell Line

Platform:: GPL16791
Series:: GSE69656

Sample

Accession:: GSM1705380

ID:: 301705380

SRA Run Selector

Select item 30170537913.

293 PTBP1 and PTBP2 double knockdown with full-length PTBP1 overexpression_rep1

Organism:: Homo sapiens

Source name:: Flp-In™ T-REx™ 293 Cell Line

Platform:: GPL16791
Series:: GSE69656

Sample

Accession:: GSM1705379

ID:: 301705379

SRA Run Selector

Select item 30170537814.

293 PTBP1 and PTBP2 double knockdown_rep2

Organism:: Homo sapiens

Source name:: Flp-In™ T-REx™ 293 Cell Line

Platform:: GPL16791
Series:: GSE69656

Sample

Accession:: GSM1705378

ID:: 301705378

SRA Run Selector

Select item 30170537715.

293 PTBP1 and PTBP2 double knockdown_rep1

Organism:: Homo sapiens

Source name:: Flp-In™ T-REx™ 293 Cell Line

Platform:: GPL16791
Series:: GSE69656

Sample

Accession:: GSM1705377

ID:: 301705377

SRA Run Selector

Select item 30170537616.

293 control knockdown_rep2

Organism:: Homo sapiens

Source name:: Flp-In™ T-REx™ 293 Cell Line

Platform:: GPL16791
Series:: GSE69656

Sample

Accession:: GSM1705376

ID:: 301705376

SRA Run Selector

Select item 30170537517.

293 control knockdown_rep1

Organism:: Homo sapiens

Source name:: Flp-In™ T-REx™ 293 Cell Line

Platform:: GPL16791
Series:: GSE69656

Sample

Accession:: GSM1705375

ID:: 301705375

SRA Run Selector

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