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Items: 1 to 20 of 54

1.

Chromosomal instability promotes metastasis through a cytosolic DNA response

(Submitter supplied) Chromosomal instability (CIN) is a hallmark of cancer, and it results from ongoing errors in chromosome segregation during mitosis. While CIN is a major driver of tumor evolution, its role in metastasis has not been established. Here we show that CIN promotes metastasis by sustaining a tumor-cell autonomous inflammatory response to cytosolic DNA. Errors in chromosome segregation create a preponderance of micronuclei whose envelopes frequently rupture exposing their DNA content to the cytosol. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL16791 GPL20301
51 Samples
Download data: CSV
Series
Accession:
GSE98183
ID:
200098183

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 4000 (Homo sapiens)

Organism:
Homo sapiens
8771 Series
200001 Samples
Download data
Platform
Accession:
GPL20301
ID:
100020301

3.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
12448 Series
356115 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

4.

MKH

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL16791
Series:
GSE98183
Download data
Sample
Accession:
GSM2589024
ID:
302589024

SRA Run Selector

5.

MK

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL16791
Series:
GSE98183
Download data
Sample
Accession:
GSM2589023
ID:
302589023

SRA Run Selector

6.

Kb

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL16791
Series:
GSE98183
Download data
Sample
Accession:
GSM2589022
ID:
302589022

SRA Run Selector

7.

Ka

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL16791
Series:
GSE98183
Download data
Sample
Accession:
GSM2589021
ID:
302589021

SRA Run Selector

8.

cont

Organism:
Homo sapiens
Source name:
Human cell line
Platform:
GPL16791
Series:
GSE98183
Download data
Sample
Accession:
GSM2589020
ID:
302589020

SRA Run Selector

9.

Contorl Brain met 31

Organism:
Homo sapiens
Source name:
Mouse xenograft
Platform:
GPL20301
Series:
GSE98183
Download data
Sample
Accession:
GSM2724465
ID:
302724465

SRA Run Selector

10.

Kif2b Brain met 32

Organism:
Homo sapiens
Source name:
Mouse xenograft
Platform:
GPL20301
Series:
GSE98183
Download data
Sample
Accession:
GSM2724464
ID:
302724464

SRA Run Selector

11.

Control Bone met 72

Organism:
Homo sapiens
Source name:
Mouse xenograft
Platform:
GPL20301
Series:
GSE98183
Download data
Sample
Accession:
GSM2724463
ID:
302724463

SRA Run Selector

12.

Control Bone 36

Organism:
Homo sapiens
Source name:
Mouse xenograft
Platform:
GPL20301
Series:
GSE98183
Download data
Sample
Accession:
GSM2724462
ID:
302724462

SRA Run Selector

13.

Control Brain 36

Organism:
Homo sapiens
Source name:
Mouse xenograft
Platform:
GPL20301
Series:
GSE98183
Download data
Sample
Accession:
GSM2724461
ID:
302724461

SRA Run Selector

14.

Control Lung 35

Organism:
Homo sapiens
Source name:
Mouse xenograft
Platform:
GPL20301
Series:
GSE98183
Download data
Sample
Accession:
GSM2724460
ID:
302724460

SRA Run Selector

15.

Control brain 35

Organism:
Homo sapiens
Source name:
Mouse xenograft
Platform:
GPL20301
Series:
GSE98183
Download data
Sample
Accession:
GSM2724459
ID:
302724459

SRA Run Selector

16.

Kif2b Bone met 32

Organism:
Homo sapiens
Source name:
Mouse xenograft
Platform:
GPL20301
Series:
GSE98183
Download data
Sample
Accession:
GSM2724458
ID:
302724458

SRA Run Selector

17.

Kif2a Adrenal met 56

Organism:
Homo sapiens
Source name:
Mouse xenograft
Platform:
GPL20301
Series:
GSE98183
Download data
Sample
Accession:
GSM2724457
ID:
302724457

SRA Run Selector

18.

Control brain met 31

Organism:
Homo sapiens
Source name:
Mouse xenograft
Platform:
GPL20301
Series:
GSE98183
Download data
Sample
Accession:
GSM2724456
ID:
302724456

SRA Run Selector

19.

Kif2a brain met 56

Organism:
Homo sapiens
Source name:
Mouse xenograft
Platform:
GPL20301
Series:
GSE98183
Download data
Sample
Accession:
GSM2724455
ID:
302724455

SRA Run Selector

20.

MCAK-Hypir Xeno 12

Organism:
Homo sapiens
Source name:
Mouse xenograft
Platform:
GPL20301
Series:
GSE98183
Download data
Sample
Accession:
GSM2724454
ID:
302724454

SRA Run Selector

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