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Items: 3

1.

Signaling Pathways Deferentially Affect RNA Polymerase II Initiation, Pausing, and Elongation in Human Cells: Estrogen dependent signaling in MCF-7 cells

(Submitter supplied) We used Global Run-on and Sequencing (GRO-seq) to measure the rate of transcription elongation by RNA polymerase II (Pol II) following gene activation. We observed that Pol II elongation rates can vary as much as 4-fold at different genomic loci and in response to two distinct cellular signaling pathways (i.e., estrogen and TNFα). Elongation rates are slowest near the promoter and increase during the first ~15 kb transcribed into the gene body. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
11 Samples
Download data: BED, TSV, TXT
Series
Accession:
GSE41324
ID:
200041324

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10422 Series
180547 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

GRO-seq_E2_40m_MCF7_1

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL11154
Series:
GSE41324
Download data: BED
Sample
Accession:
GSM1014645
ID:
301014645

SRA Run Selector

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db=gds|term=GSM1014645[Accession]|query=1|qty=2|blobid=MCID_6664359bac4a2c1050dd35fd|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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