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Items: 3

1.

Genome-wide maps of WT and over-expressing CenH3/CENP-A in Human HeLa S3 cells

(Submitter supplied) Centromeres are essential to ensure proper chromosome segregation in eukaryotes. Their definition relies on the presence of a centromere-specific H3 histone variant CenH3, known as CENP-A in mammals. Its overexpression in aggressive cancers raises questions concerning its effect on chromatin dynamics and contribution to tumorigenesis. We find that CenH3 overexpression in human cells leads to ectopic enrichment at sites of active histone turnover. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platform:
GPL11154
16 Samples
Download data: BED, TXT, WIG
Series
Accession:
GSE42951
ID:
200042951
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

WT MNase input (replicate 2)

Organism:
Homo sapiens
Source name:
WT MNase input
Platform:
GPL11154
Series:
GSE42951
Download data: WIG
Sample
Accession:
GSM1053818
ID:
301053818
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